Browse our Tools and Resources

Page 30 of 83
    1. Biochemistry and Chemical Biology
    2. Neuroscience

    Precise optical control of gene expression in C elegans using improved genetic code expansion and Cre recombinase

    Lloyd Davis, Inja Radman ... Sebastian Greiss
    A method combining optimised genetic code expansion and optogenetics allows dissection of neural circuits with single-cell precision in freely moving animals.
    1. Computational and Systems Biology

    PARROT is a flexible recurrent neural network framework for analysis of large protein datasets

    Daniel Griffith, Alex S Holehouse
    PARROT makes it easy for anyone to train and use system- or data-specific deep learning models that map between protein sequence and arbitrary sequence annotations.
    1. Immunology and Inflammation

    Ascorbic acid supports ex vivo generation of plasmacytoid dendritic cells from circulating hematopoietic stem cells

    Anders Laustsen, Renée M van der Sluis ... Rasmus O Bak
    Probing of various culture conditions leads to fundamental advances in ex vivo production of plasmacytoid dendritic cells for use in immunotherapy.
    1. Neuroscience

    The BigBrainWarp toolbox for integration of BigBrain 3D histology with multimodal neuroimaging

    Casey Paquola, Jessica Royer ... Boris Bernhardt
    The BigBrainWarp toolbox facilitates integration of 3D human brain histology with neuroimaging, helping neuroscientists to utilise cytoarchitectural information in conjunction with in vivo imaging.
    1. Neuroscience

    Classification and genetic targeting of cell types in the primary taste and premotor center of the adult Drosophila brain

    Gabriella R Sterne, Hideo Otsuna ... Kristin Scott
    A split-GAL4 collection provides precise genetic targeting of 138 neuronal cell types in the subesophageal zone of adult Drosophila melanogaster.
    1. Genetics and Genomics
    2. Neuroscience

    Scaled, high fidelity electrophysiological, morphological, and transcriptomic cell characterization

    Brian R Lee, Agata Budzillo ... Jim Berg
    High-quality, multimodal, electrophysiological, morphological, and transcriptomic data collection from a single cell using a refined Patch-seq protocol.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    A precisely adjustable, variation-suppressed eukaryotic transcriptional controller to enable genetic discovery

    Asli Azizoglu, Roger Brent, Fabian Rudolf
    A new gene expression tool enables precise control of protein dosage over a large range and paves the way for new genetic discoveries.
    1. Cell Biology
    2. Developmental Biology

    Imaging cytoplasmic lipid droplets in vivo with fluorescent perilipin 2 and perilipin 3 knock-in zebrafish

    Meredith H Wilson, Stephen C Ekker, Steven A Farber
    Fluorescent perilipin zebrafish lines are powerful new tools for studying lipid droplet dynamics in health and disease.
    1. Neuroscience

    Scanned optogenetic control of mammalian somatosensory input to map input-specific behavioral outputs

    Ara Schorscher-Petcu, Flóra Takács, Liam E Browne
    A system to generate ‘remote touch’ in freely behaving mice can be utilized to map behavior caused by precise somatosensory inputs.
    1. Microbiology and Infectious Disease
    2. Plant Biology

    Host-associated microbe PCR (hamPCR) enables convenient measurement of both microbial load and community composition

    Derek S Lundberg, Pratchaya Pramoj Na Ayutthaya ... Detlef Weigel
    hamPCR is a cost-effective and transformative amplicon sequencing strategy to describe microbiota composition and measure its overall abundance, applicable to all samples in which host and microbial DNA are co-extracted.