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Page 42 of 92
    1. Cell Biology

    An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish

    Dianne Lumaquin, Eleanor Johns ... Richard M White
    A novel transgenic lipid droplet reporter in transparent casper zebrafish allows direct visualization of individual lipid droplets in a living animal.
    1. Computational and Systems Biology
    2. Genetics and Genomics

    Detecting adaptive introgression in human evolution using convolutional neural networks

    Graham Gower, Pablo Iáñez Picazo ... Fernando Racimo
    Convolutional neural networks are an effective tool for detecting archaic adaptive introgression from genomic data.
    1. Neuroscience

    Introduction to the EQIPD quality system

    Anton Bespalov, René Bernard ... Thomas Steckler
    A system has been developed that supports generation of reliable basic biomedical research data while being open-access and lean with no negative impact on freedom of scientific exploration.
    1. Neuroscience

    Cross-species analysis defines the conservation of anatomically segregated VMH neuron populations

    Alison H Affinati, Paul V Sabatini ... Alan C Rupp
    This atlas and analysis of conserved ventromedial hypothalamic nucleus (VMH) neuron populations provides an unbiased starting point for the analysis of VMH circuitry and function.
    1. Neuroscience

    Metal microdrive and head cap system for silicon probe recovery in freely moving rodent

    Mihály Vöröslakos, Peter C Petersen ... György Buzsáki
    A reusable system of 3D printed stainless steel microdrive and plastic head cap allows stable recording of electrophysiological data in mice and rats and easy recovery of silicon probes.
    1. Neuroscience

    Optogenetic strategies for high-efficiency all-optical interrogation using blue-light-sensitive opsins

    Angelo Forli, Matteo Pisoni ... Tommaso Fellin
    A new soma-targeted variant of the large-conductance blue-light-sensitive opsin CoChR combined with advanced optical stimulation methods allows high-efficiency all-optical neuronal imaging and stimulation in mouse brain in vivo.
    1. Developmental Biology

    Live-imaging of endothelial Erk activity reveals dynamic and sequential signalling events during regenerative angiogenesis

    Kazuhide S Okuda, Mikaela S Keyser ... Benjamin M Hogan
    Live-imaging of a transgenic reporter of vascular Erk signalling in zebrafish reveals sequential signalling mechanisms during the initiation of regeneration in wounded blood vessels.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A subcellular map of the human kinome

    Haitao Zhang, Xiaolei Cao ... Bin Zhao
    An immunofluorescent analysis of 465 protein kinases revealed a substantial role of liquid-liquid phase separation in kinase localization and identified new kinase localizations to mitochondria and other organelles.
    1. Neuroscience

    EEG-based detection of the locus of auditory attention with convolutional neural networks

    Servaas Vandecappelle, Lucas Deckers ... Tom Francart
    Convolutional neural networks can decode whether a person is listening to a speaker on the left or right solely from 1 to 2s of EEG data.
    1. Cell Biology
    2. Computational and Systems Biology

    Artistoo, a library to build, share, and explore simulations of cells and tissues in the web browser

    Inge MN Wortel, Johannes Textor
    By letting users build interactive simulations directly in a web browser, Artistoo unlocks new ways to communicate, teach, and collaborate in computational biology research.