Browse our Tools and Resources

Page 43 of 83
    1. Neuroscience

    A flexible framework for simulating and fitting generalized drift-diffusion models

    Maxwell Shinn, Norman H Lam, John D Murray
    Sophisticated decision-making mechanisms and complex experimental paradigms can be modeled, simulated, and fit to empirical response time data, using a flexible and efficient computational modeling framework.
    1. Biochemistry and Chemical Biology

    How to measure and evaluate binding affinities

    Inga Jarmoskaite, Ishraq AlSadhan ... Daniel Herschlag
    Simple guidelines and a checklist are provided for performing high-quality equilibrium binding measurements.
    1. Plant Biology

    Accurate and versatile 3D segmentation of plant tissues at cellular resolution

    Adrian Wolny, Lorenzo Cerrone ... Anna Kreshuk
    Convolutional neural networks and graph partitioning algorithms can be combined into an easy-to-use tool for segmentation of cells in dense plant tissue volumes imaged with light microscopy.
    1. Computational and Systems Biology
    2. Evolutionary Biology

    A community-maintained standard library of population genetic models

    Jeffrey R Adrion, Christopher B Cole ... Andrew D Kern
    The stdpopsim library, a community-driven open source project, is presented which provides easy access to a standard catalog of published simulation models for population genetics aimed at field-wide standardization.
    1. Neuroscience

    A machine-vision approach for automated pain measurement at millisecond timescales

    Jessica M Jones, William Foster ... Ishmail Abdus-Saboor
    Development of a fully automated pain scale using machine learning tools in computational neuroethology and creation of new software, reveals a robust circuit-dissection compatible platform for objective pain measurement.
    1. Neuroscience
    2. Physics of Living Systems

    Revealing architectural order with quantitative label-free imaging and deep learning

    Syuan-Ming Guo, Li-Hao Yeh ... Shalin B Mehta
    Advances in quantitative phase and polarized light microscopy, combined with deep learning, reveal the architecture of human brain tissue.
    1. Developmental Biology
    2. Genetics and Genomics

    An atlas of cell types in the mouse epididymis and vas deferens

    Vera D Rinaldi, Elisa Donnard ... Oliver J Rando
    A systematic survey of the epididymis identifies the cell types involved in post-testicular maturation of sperm.
    1. Neuroscience

    Improving a probabilistic cytoarchitectonic atlas of auditory cortex using a novel method for inter-individual alignment

    Omer Faruk Gulban, Rainer Goebel ... Federico de Martino
    Inter-individual human brain alignment that uses macro-anatomical priors in addition to cortical curvature improves micro-anatomical correspondence between auditory areas.
    1. Cell Biology
    2. Genetics and Genomics

    A high-throughput small molecule screen identifies farrerol as a potentiator of CRISPR/Cas9-mediated genome editing

    Weina Zhang, Yu Chen ... Zhiyong Mao
    Farrerol promotes the efficiency of CRISPR/Cas9-mediated genome editing in both cells and embryos.
    1. Immunology and Inflammation
    2. Neuroscience

    A new genetic strategy for targeting microglia in development and disease

    Gabriel L McKinsey, Carlos O Lizama ... Thomas D Arnold
    P2ry12-CreER robustly and specifically labels microglia in fate-mapping and ribosomal profiling experiments, revealing new markers for myeloid subpopulations in the central nervous system.