Andrea Cuentas-Condori, Ben Mulcahy ... David M Miller III
Caenorhabditis elegans has bona fide dendritic spines, suggesting that the advantages of small model organisms, such as genetic manipulations and live-cell imaging, can be exploited to study dendritic spines.
Using different sets of input sequences to evolutionary reconstruction algorithms results in the exploration of many possible models, the intergration over which produces significantly more accurate models.
An iterative self-assembling algorithm identifies the intrinsic structures in single-cell transcriptomic data and helps to discover new cell populations that are undetectable by existing methods.
Andrea Mair, Shou-Ling Xu ... Dominique C Bergmann
Proximity-labeling using engineered biotin ligases TurboID and miniTurbo enables detection of cell-type-specific and low abundance protein complexes and subcellular proteomes in Arabidopsis and other plants.
José Muñoz-Dorado, Aurelio Moraleda-Muñoz ... Juana Pérez
Investigation of global gene expression profiles during formation of the Myxococcus xanthus specialized biofilm reveals a genetic regulatory network that coordinates cell motility, differentiation, and secondary metabolite production.
Brian 2 is a software package for neural simulations that makes it both easy and computationally efficient to define original models for computational experiment.
Nanobodies are developed that target neuronal proteins with restricted subcellular distributions and used as intrabodies to deliver cargo to specific sites within neurons and nanoscale immunolabels for improved imaging resolution.