Kira A Cozzolino, Lynn Sanford ... Dylan J Taatjes
The Mediator-associated kinases CDK8 and CDK19 help drive inflammatory responses to interferon, and it is discovered that kinase-dependent transcriptional responses manifest in part through splicing changes and lipid metabolites.
Kazi A Hossain, Lukasz Nierzwicki ... Giulia Palermo
xCas9's ability to recognise diverse DNA sequences stems from structural flexibility in the protospacer adjacent motif (PAM)-interacting cleft and adaptability to PAM-induced conformational changes, paving the way for advanced genome editing tools.
Audiomotor mismatch responses in auditory cortex are amplified by concurrent visuomotor mismatches, highlighting non-hierarchical and multimodal processing of prediction errors.
Marina Padilha, Victor Nahuel Keller ... Gilberto Kac
A panel of serum biomarkers, including dietary and microbial-derived metabolites related to the gut-brain axis, were identified as potential for tracking children at risk of early childhood developmental delays.
