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Page 15 of 1,818
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    Atomistic simulation of voltage activation of a truncated BK channel

    Zhiguang Jia, Jianhan Chen
    Ten-microsecond atomistic simulations directly capture the voltage activation of the Core-MT big potassium channel, revealing novel voltage sensing and sensor-pore coupling mechanisms that have largely eluded the community.
    1. Neuroscience

    RubyACRs Enable Red-Shifted Optogenetic Inhibition in Freely Behaving Drosophila

    Daniel Bushey, Hiroshi Shiozaki ... Glenn C Turner
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Common psychiatric treatments alter affective dynamics

    Quentin Dercon, Quentin JM Huys ... Camilla L Nord
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    PPARγ mediated enhanced lipid biogenesis fuels Mycobacterium tuberculosis growth in a drug-tolerant hepatocyte environment

    Binayak Sarkar, Jyotsna ... Rajesh S Gokhale
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Cell Biology

    Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response

    Akinori Endo, Chikage Takahashi ... Yukiko Yoshida
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Microbiology and Infectious Disease

    Mycobacterial Metallophosphatase MmpE Acts as a Nucleomodulin to Regulate Host Gene Expression and Promote Intracellular Survival

    Liu Chen, Baojie Duan ... Aizhen Guo
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    IFIT1 is rapidly evolving and exhibits disparate antiviral activities across 11 mammalian orders

    Matthew B McDougal, Ian N Boys ... John W Schoggins
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    Pathogenic O-GlcNAc dyshomeostasis associated with cortical malformations and hyperactivity

    Florence Authier, Asad Jan ... Daan MF van Aalten
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Cell Biology

    Matrix-associated extracellular vesicles modulate smooth muscle cell adhesion and directionality by presenting collagen VI

    Alexander Kapustin, Sofia Serena Tsakali ... Catherine M Shanahan
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    The Mycobacterium tuberculosis complex pangenome is small and shaped by sub-lineage-specific regions of difference

    Mahboobeh Behruznia, Maximillian Marin ... Conor J Meehan
    The accessory genome of Mycobacterium tuberculosis is small, but differences in gene content are found both between and within lineages.
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