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Page 16 of 1,780
    1. Cell Biology
    2. Neuroscience

    Heterozygosity for neurodevelopmental disorder-associated TRIO variants yields distinct deficits in behavior, neuronal development, and synaptic transmission in mice

    Yevheniia Ishchenko, Amanda T Jeng ... Anthony J Koleske
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Unravelling the neurocognitive mechanisms underlying counterconditioning in humans

    Lisa Wirz, Maxime C Houtekamer ... Erno J Hermans
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    SIRT2-mediated ACSS2 K271 deacetylation suppresses lipogenesis under nutrient stress

    Rezwana Karim, Wendi Teng ... Hening Lin
    A cross-talk is revealed between two branches of metabolisms, amino acid limitation suppressing fatty acid biosynthesis, via posttranslational modifications of an enzyme involved in fatty acid biosynthesis.
    1. Cell Biology

    MARK2 regulates Golgi apparatus reorientation by phosphorylation of CAMSAP2 in directional cell migratio

    Peipei Xu, Rui Zhang ... Wenxiang Meng
    MARK2-mediated phosphorylation of CAMSAP2 dynamically controls Golgi orientation by altering microtubule anchoring and polarity during directional cell migration.
    1. Cancer Biology

    KDM5 demethylases suppress R-loop-mediated “viral mimicry” and DNA damage in breast cancer cells

    Lena Lau, Kurt Henderson ... Marie Classon
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Single-cell type analysis of wing premotor circuits in the ventral nerve cord of Drosophila melanogaster

    Erica Ehrhardt, Samuel C Whitehead ... Wyatt Korff
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cancer Biology

    The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells

    Jie Fang, Shivendra Singh ... Jun Yang
    Drastic differences in genetic and epigenetic fitness of MYC-driven cancer cells in 3D vs 2D culture.
    Version of Record
    Research Article
    • Important
    • Convincing
    • Incomplete
    1. Immunology and Inflammation

    RAG suppresses group 2 innate lymphoid cells

    Aaron M Ver Heul, Madison Mack ... Brian S Kim
    Developmental imprinting controls innate type 2 immune function and allergic inflammation.
    1. Cell Biology

    Reprograming gene expression in ‘hibernating’ C. elegans involves the IRE-1/XBP-1 pathway

    Melanie Lianne Engelfriet, Yanwu Guo ... Rafal Ciosk
    Gene expression in nematodes during cold-induced dormancy is proposed to be regulated at the transcription level, partly involving the activation of unfolded protein response (UPR) through the IRE-1/XBP-1 signaling pathway.
    1. Developmental Biology
    2. Evolutionary Biology

    Differences in size and number of embryonic type II neuroblast lineages correlate with divergent timing of central complex development between beetle and fly

    Simon Rethemeier, Sonja Fritzsche ... Vera S Hunnekuhl
    Genetic labeling and molecular analyses characterize the dynamics of embryonic central complex-forming type II neuroblast lineages in Tribolium castaneum.