Browse the latest research

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    1. Microbiology and Infectious Disease

    Longitudinal transcriptional changes reveal genes from the natural killer cell-mediated cytotoxicity pathway as critical players underlying COVID-19 progression

    Matias A Medina, Francisco Fuentes-Villalobos ... Maria Ines Barria
    Longitudinal transcriptomic analysis of unvaccinated patients reveals that early NK cell cytotoxicity activation distinguishes mild from severe COVID-19, supporting the relevance of concerted innate–adaptive immune responses against the virus.
    1. Neuroscience

    Cestode larvae excite host neuronal circuits via glutamatergic signaling

    Anja de Lange, Hayley Tomes ... Joseph V Raimondo
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Convincing
    1. Neuroscience

    Mitochondrial calcium modulates odor-mediated behavioral plasticity in C. elegans

    Hee Kyung Lee, Dong-Kyu Joo ... Kyoung-hye Yoon
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Neuroscience

    Cellular and circuit features distinguish dentate gyrus semilunar granule cells and granule cells activated during contextual memory formation

    Laura Dovek, Krista Marrero ... Vijayalakshmi Santhakumar
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology

    Molecular and Mechanical Signatures Contributing to Epidermal Differentiation and Barrier Formation

    Alexandra Prado-Mantilla, Wenxiu Ning, Terry Lechler
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Neuroscience

    Development of a Marmoset Apparatus for Automated Pulling to study cooperative behaviors

    Olivia C Meisner, Weikang Shi ... Steve WC Chang
    The Marmoset Apparatus for Automated Pulling provides a powerful and scalable experimental platform for studying behavioral and neural mechanisms underlying cooperation in freely moving marmosets.
    1. Cancer Biology

    The T cell receptor β chain repertoire of tumor infiltrating lymphocytes improves neoantigen prediction and prioritization

    Thi Mong Quynh Pham, Thanh Nhan Nguyen ... Le Son Tran
    The integration of pHLA binding and pHLA-TCR analysis effectively improves the precision of insilico neoantigen prioritization, potentially enhancing personalized immunotherapies for colorectal cancer.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Large-scale analysis of the integration of enhancer-enhancer signals by promoters

    Miguel Martinez-Ara, Federico Comoglio, Bas van Steensel
    A high-throughput enhancer-enhancer-promoter reporter assay indicates that pairs of enhancers generally activate promoters in a near-additive manner, and that promoters transform their collective effect non-linearly.
    1. Immunology and Inflammation

    Nuclear receptor corepressor 1 controls regulatory T cell subset differentiation and effector function

    Valentina Stolz, Rafael de Freitas e Silva ... Wilfried Ellmeier
    The transcriptional adapter protein NCOR1 that links chromatin-modifying enzymes with gene-specific transcription factors controls naive and effector regulatory T cell states.
    1. Neuroscience

    Regional response to light illuminance across the human hypothalamus

    Islay Campbell, Roya Sharifpour ... Gilles Vandewalle
    Distinct local dynamics of different hypothalamus areas were detected in response to changing illuminance and could contribute to light’s impact on cognition.
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