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    1. Biochemistry and Chemical Biology
    2. Immunology and Inflammation

    One N-glycan regulates natural killer cell antibody-dependent cell-mediated cytotoxicity and modulates Fc γ receptor IIIa/CD16a structure

    Paul G Kremer, Elizabeth A Lampros ... Adam W Barb
    Multiple lines of evidence demonstrate that a single N-glycan on one receptor influences the strength of a cytotoxic response elicited by natural killer cells following stimulation with an antibody-coated target.
    1. Cell Biology

    GDF2 and BMP10 coordinate liver cellular crosstalk to maintain liver health

    Dianyuan Zhao, Ziwei Huang ... Li Tang
    Hepatic stellate cells play a central role in maintaining liver health by mediating cell-to-cell crosstalk via the production of GDF2 and BMP10.
    1. Neuroscience

    Increasing adult-born neurons protects mice from epilepsy

    Swati Jain, John J LaFrancois ... Helen E Scharfman
    Increasing adult-born neurons in the dentate gyrus reduces neuronal loss and chronic seizures in female mice using a mouse model of temporal lobe epilepsy.
    1. Cell Biology

    Actin dynamics switches two distinct modes of endosomal fusion in yolk sac visceral endoderm cells

    Seiichi Koike, Masashi Tachikawa ... Masayuki Masu
    There are two distinct modes of late endosome fusion in the mouse yolk sac visceral endoderm cells and actin dynamics plays a role in regulating vesicle fusion.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Somatic mutation rates scale with time not growth rate in long-lived tropical trees

    Akiko Satake, Ryosuke Imai ... Masahiro Kasahara
    Long-lived tropical trees in Southeast Asia accumulate somatic mutations in a manner that is dependent on time, rather than growth rate.
    1. Neuroscience

    Scale matters: Large language models with billions (rather than millions) of parameters better match neural representations of natural language

    Zhuoqiao Hong, Haocheng Wang ... Ariel Goldstein
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Neuroscience

    Characterization of Postsynaptic Glutamate Transporter Functionality in the Zebrafish Retinal First Synapse Across Different Wavelengths

    Marco Garbelli, Stephanie Niklaus, Stephan CF Neuhauss
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    Membrane potential modulates ERK activity and cell proliferation

    Mari Sasaki, Masanobu Nakahara ... Fumihito Ono
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Incomplete
    1. Neuroscience

    Distinct gradients of cortical architecture capture visual representations and behavior across the lifespan

    Xiayu Chen, Xingyu Liu ... Jesse Gomez
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Compelling
    • Incomplete
    1. Stem Cells and Regenerative Medicine

    Correction: Context-dependent modification of PFKFB3 in hematopoietic stem cells promotes anaerobic glycolysis and ensures stress hematopoiesis

    Shintaro Watanuki, Hiroshi Kobayashi ... Keiyo Takubo
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