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    1. Cell Biology
    2. Developmental Biology

    Wnt induces FZD5/8 endocytosis and degradation and the involvement of RSPO-ZNRF3/RNF43 and DVL

    Dong Luo, Jing Zheng ... Xinjun Zhang
    RSPO-ZNRF3/RNF43 specifically regulates the degradation of FZD5/8 under Wnt stimulation independently of DVL.
    1. Immunology and Inflammation

    Metabolic regulation of immune memory and function of microglia

    Nikolaos Nirakis, Sofia Dimothyra ... Vasileia Ismini Alexaki
    Cell metabolic processes, particularly glucose, glutamine, and lipid metabolism, orchestrate inflammatory responses and promote epigenetic changes shaping microglia immune memory.
    1. Plant Biology

    Life-cycle-related gene expression patterns in the brown algae

    Pélagie Ratchinski, Olivier Godfroy ... J Mark Cock
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    When word order matters: human brains represent sentence meaning differently from large language models

    James Fodor, Carsten Murawski, Shinsuke Suzuki
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Evolutionary Biology

    Evolutionary Adaptations of IRG1 Refines Itaconate Synthesis and Mitigates Innate Immunometabolism Trade-offs

    Richard V Szeligowski, Francois Miros ... Hongying Shen
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Neuroscience

    Functional connectivity, structural connectivity, and inter-individual variability in Drosophila melanogaster

    Takuto Okuno, Alexander Woodward ... Junichi Hata
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience
    2. Physics of Living Systems

    A Deep Learning Pipeline for Mapping in situ Network-level Neurovascular Coupling in Multi-photon Fluorescence Microscopy

    Matthew Rozak, James Mester ... Bojana Stefanovic
    Revised
    Reviewed Preprint v4
    Updated
    • Valuable
    • Solid
    1. Neuroscience

    Generation of knock-in Cre and FlpO mouse lines for precise targeting of striatal projection neurons and dopaminergic neurons

    Eddy Albarran, Akira Fushiki ... Rui M Costa
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    • Incomplete
    1. Microbiology and Infectious Disease

    Heterogeneity of Genetic Sequence within Quasi-species of Influenza Virus Revealed by Single-Molecule Sequencing

    Kenji Tamao, Hiroyuki Noji, Kazuhito V Tabata
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Computational and Systems Biology

    TrueProbes: Quantitative Single-Molecule RNA-FISH Probe Design Improves RNA Detection

    Jason J Hughes, Benjamin K Kesler ... Gregor Neuert
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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