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    1. Neuroscience

    Synaptic connectome of a neurosecretory network in the Drosophila brain

    Theresa H McKim, Jayati Gera ... Meet Zandawala
    Connectome-level analysis of the Drosophila neuroendocrine system reveals the organizational logic by which the brain integrates sensory information to regulate hormonal signaling.
    1. Developmental Biology

    Svep1 orchestrates distal airway patterning and alveolar differentiation in murine lung development

    Nicole Foxworth, Julie Wells ... Maria Loscertales
    Genetic and functional analyses identify SVEP1 as an extracellular matrix regulator that coordinates airway branching, smooth muscle differentiation, and alveolar maturation during lung development.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Zebrafish Rif1 impacts zygotic genome activation, replication timing, and sex determination

    Emily A Masser, Tyler D Noble ... Christopher L Sansam
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Gene function and expression profiling in yeast spores, killifish diapause embryos, and their post-dormant offspring cells

    Shaimaa Hassan, Maria Rodriguez-López ... Jürg Bähler
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Microbiology and Infectious Disease

    Structures of LolB bound to LolA or lipoprotein resolve the final steps of bacterial lipoprotein trafficking

    Abigail E Jepson, Elise Kaplan ... Vassilis Koronakis
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    • Incomplete
    1. Biochemistry and Chemical Biology
    2. Evolutionary Biology

    Sequence adaptations satisfy the constraints of mitochondrial membrane protein evolution

    Tarun Yadav, Jonathan H Borowsky ... Jared Rutter
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    P95-HER2 promotes metastatic progression by biasing MRTFA dependent signaling

    Joseph D Fernandes, Erin Bresnahan ... Joshua C Snyder
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Developmental Biology
    2. Neuroscience

    Neurotrophin-3 produced by motor neurons non-cell autonomously regulates the development of pre-motor interneurons in the developing spinal cord

    Andrea Angla-Navarro, Ana Dominguez Bajo ... Frédéric Clotman
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    1. Genetics and Genomics
    2. Plant Biology

    AT-HOOK-MOTIF NUCLEAR LOCALIZED 15 extends plant longevity by binding at poorly accessible, epigenetic mark-depleted chromatin surrounding transcribed regions

    Thalia Luden, Jihed Chouaref, Remko Offringa
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression

    Mediator subunit MED16 cooperates with UBP1-TFCP2 to control the promoter context-dependent transcriptional activity

    Yuan-Ming Zheng, Xia-Ying Zhao ... Gang Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
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