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A critical re-evaluation of some of the quintessential examples given as evidence for cortical reorganisation argues that, contrary to the prevalent view, any opportunities for functional change in cortical organisation are incremental and constrained by the underlying structural ‘blueprint'.

A comprehensive comparison of the two types of pancreatic cancer symptom trajectories can in combination leverage a fuller potential of large health data and ultimately aid the detection of early risk factors for pancreatic cancer.

Six-transmembrane epithelial antigen of the prostate isoform 1 (STEAP1) can establish a physiologically relevant electron transfer chain and STEAP2 can transfer electrons via a diffusible FAD mechanism.

Single-cell transcriptomics of larval zebrafish spinal cord reveal ion channels and exocytotic machinery that enhance transmitter release in neuronal types shown to mediate high-speed swimming and escape behavior.

Structural predictions using AlphaFold suggest a mechanism by which Wapl mediates cohesin's dissociation from chromatin, a process whose downregulation is essential for VDJ recombination and diverse protocadherin gene expression.

Deciding which of two perceptual decisions is more difficult involves sequential sampling processes that terminate when the difference in accumulated evidence for each decision exceeds a threshold.

The pre-Bötzinger complex, known as the kernel for the breathing generation, consists of separate subpopulations of neurons that project to specific nuclei to coordinate respiratory rhythmicity with different physiological behaviors, such as nasofacial activity.

Cyclin D1 protein stability is regulated by ubiquitin-proteasome mechanism mediated by multiple E3 ligases, including newly identified Keap1, DDB2, and WSB2.