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Page 379 of 1,792
    1. Cell Biology

    Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp

    Abigail C Neininger-Castro, James B Hayes ... Dylan Tyler Burnette
    Software is introduced for the rapid and comprehensive quantification of sarcomere-containing myofibrils and their precursors in cardiac myocytes, aiding in the advancement of cardiovascular cell biology investigations.
    1. Neuroscience

    Motor actions are spatially organized in motor and dorsal premotor cortex

    Nicholas G Chehade, Omar A Gharbawie
    The spatial dimension of neural activity is an organizing feature of the neural code that controls motor actions.
    1. Cell Biology
    2. Medicine

    Increase of cell surface vimentin is associated with vimentin network disruption and subsequent stress-induced premature senescence in human chondrocytes

    Jana Riegger, Rolf E Brenner
    Disruption of the intracellular vimentin network upon cellular stress results in enhanced cell surface vimentin on human osteoarthritic chondrocytes and might represent a novel membrane-associated marker of stress-induced premature senescence.
    1. Cancer Biology
    2. Epidemiology and Global Health

    Risk of second primary cancers after a diagnosis of first primary cancer: A pan-cancer analysis and Mendelian randomization study

    Xiaohao Ruan, Da Huang ... Rong Na
    A certain type of primary cancer may cause another second primary cancer which would be of clinical importance to make a personalized screening plan for certain primary cancer patients.
    1. Immunology and Inflammation

    De novo fatty-acid synthesis protects invariant NKT cells from cell death, thereby promoting their homeostasis and pathogenic roles in airway hyperresponsiveness

    Jaemoon Koh, Yeon Duk Woo ... Doo Hyun Chung
    The development and functionalities of invariant natural-killer T cells are dependent upon their cell-intrinsic ACC1-mediated de novo fatty acid synthesis, which greatly affect outcomes of allergic asthma.
    1. Computational and Systems Biology
    2. Structural Biology and Molecular Biophysics

    Myristoyl’s dual role in allosterically regulating and localizing Abl kinase

    Svenja de Buhr, Frauke Gräter
    The cellular membrane competes with Abl for myristoyl binding to stabilize the preactivated state and enhance allosteric activation.
    1. Neuroscience

    Foveated metamers of the early visual system

    William F. Broderick, Gizem Rufo ... Eero P. Simoncelli
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Incomplete
    1. Neuroscience

    Menopause, Brain Anatomy, Cognition and Alzheimer’s Disease

    Manuela Costantino, Grace Pigeau ... M. Mallar Chakravarty
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Neuroscience

    Auditory cortical error signals retune during songbird courtship

    Caleb Jones, Jesse H. Goldberg
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Experimentally induced active and quiet sleep engage non-overlapping transcriptional programs in Drosophila

    Niki Anthoney, Lucy Tainton-Heap ... Bruno van Swinderen
    Different methods for inducing sleep in Drosophila flies may be promoting distinct sleep stages with different functions when brain activity and gene expression are compared.
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