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A comparison between artificially created allopolyploids and natural ones reveals that the latter underwent significant evolutionary steps after their formation.

Multiple dynamic protein interactions converge to regulate the catalytic activity of the B cell kinase, BTK.

Immune activation in Drosophila macrophages during oxidative stress is regulated by DNA damage signaling, which controls proinflammatory cytokine release and the susceptibility of the fly to oxidative stress.

Characterization of the molecular mechanisms that enable azelaic acid, a secondary metabolite produced by photosynthetic organisms, to promote or inhibit different bacterial populations.

Combinations of inhibitors can more selectively inhibit individual or multiple protein kinases than single inhibitors.

Loss of functional dystroglycan disrupts the formation and function of CCK⁺/CB₁R⁺ inhibitory synapses in hippocampal CA1, resulting in reduced seizure thresholds in mouse models of dystroglycanopathy.

Elevated levels of ectopic fat and a decreased number of oxidative insulin-sensitive type I muscle fibers in skeletal muscle could lead to insulin resistance in women with polycystic ovary syndrome.

The structures of full-length Las1-Grc3 complexes provide crucial insights into the activation mechanism of HEPN nuclease and the pathway of pre-rRNA processing in ribosome biosynthesis.

The signaling requirements to decouple proliferation of pancreatic progenitors from differentiation were elucidated and employed for the reproducible expansion, under GMP-compliant conditions, of pancreatic progenitors derived from different human pluripotent stem cell lines.

Participants under acute stress were less willing to exert a relatively low level of physical effort for actions that benefit another person compared to actions that benefit themselves.