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Page 457 of 1,892
    1. Neuroscience

    A maximum of two readily releasable vesicles per docking site at a cerebellar single active zone synapse

    Melissa Silva, Van Tran, Alain Marty
    Counting the number of synaptic vesicles released in simple synapses under high release probability conditions revealed a maximum readily releasable pool size of two vesicles per docking site.
    1. Developmental Biology

    Homeodomain proteins hierarchically specify neuronal diversity and synaptic connectivity

    Chundi Xu, Tyler B Ramos ... Chris Q Doe
    The homeodomain protein Bsh increases lamina neuron types and visual function.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Interface-acting nucleotide controls polymerization dynamics at microtubule plus- and minus-ends

    Lauren A McCormick, Joseph M Cleary ... Luke M Rice
    Comparative measurements and simulations of microtubule plus and minus end growth with mixed nucleotides demonstrate that nucleotide acts across a tubulin:tubulin interface to influence microtubule stability and dynamics.
    1. Evolutionary Biology
    2. Microbiology and Infectious Disease

    Selection on plastic adherence leads to hyper-multicellular strains and incidental virulence in the budding yeast

    Luke I Ekdahl, Juliana A Salcedo ... Helen A Murphy
    Yeast that were evolved to adhere to plastic surfaces for a few hundred generations became hyper-adherent and more virulent.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Nicotinic acetylcholine receptor signaling maintains epithelial barrier integrity

    Nadja S Katheder, Kristen C Browder ... Heinrich Jasper
    Signaling through nicotinic acetylcholine receptors in enterocytes impacts barrier integrity in the Drosophila intestine by regulating formation of the peritrophic matrix.
    1. Neuroscience

    Modeling apical and basal tree contribution to orientation selectivity in a mouse primary visual cortex layer 2/3 pyramidal cell

    Konstantinos-Evangelos Petousakis, Jiyoung Park ... Panayiota Poirazi
    Apical and basal dendrites contribute differently to single-neuron orientation selectivity, highlighting the impact of feedforward and feedback signal interactions.
    1. Physics of Living Systems

    IS200/IS605 Family-Associated TnpB Increases Transposon Activity and Retention

    Davneet Kaur, Thomas E. Kuhlman
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Medicine
    2. Stem Cells and Regenerative Medicine

    Iron chelation improves ineffective erythropoiesis and iron overload in myelodysplastic syndrome mice

    Wenbin An, Maria Feola ... Yelena Ginzburg
    Dysregulated erythroblast-specific iron trafficking and regulation of iron metabolism provides evidence of a novel potential therapeutic target to reverse ineffective erythropoiesis in MDS.
    1. Ecology
    2. Genetics and Genomics

    Non-invasive real-time genomic monitoring of the critically endangered kākāpō

    Lara Urban, Allison K Miller ... Andrew Digby
    The application of real-time genomics by long-read nanopore sequencing to environmental samples creates a new trajectory for non-invasive genomics-based monitoring of critically endangered wildlife.