Counting the number of synaptic vesicles released in simple synapses under high release probability conditions revealed a maximum readily releasable pool size of two vesicles per docking site.
Lauren A McCormick, Joseph M Cleary ... Luke M Rice
Comparative measurements and simulations of microtubule plus and minus end growth with mixed nucleotides demonstrate that nucleotide acts across a tubulin:tubulin interface to influence microtubule stability and dynamics.
Nadja S Katheder, Kristen C Browder ... Heinrich Jasper
Signaling through nicotinic acetylcholine receptors in enterocytes impacts barrier integrity in the Drosophila intestine by regulating formation of the peritrophic matrix.
Konstantinos-Evangelos Petousakis, Jiyoung Park ... Panayiota Poirazi
Apical and basal dendrites contribute differently to single-neuron orientation selectivity, highlighting the impact of feedforward and feedback signal interactions.
Dysregulated erythroblast-specific iron trafficking and regulation of iron metabolism provides evidence of a novel potential therapeutic target to reverse ineffective erythropoiesis in MDS.
The application of real-time genomics by long-read nanopore sequencing to environmental samples creates a new trajectory for non-invasive genomics-based monitoring of critically endangered wildlife.