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Biochemical, molecular, and genetic analyses show that in Drosophila the epigenetic enzyme TET does not demethylate 6mA, which is scarce in the genome, but rather acts in a catalytic-independent manner.

Structure and simulations reveal SARS-CoV-2 NSP10 is more resistant to genetic variations than other SARS-CoV-2 NSPs and that the presence of mutations conserves structural and dynamic changes in NSP10.

Increased genetic liability to colorectal cancer is associated with altered levels of circulating metabolites, including fatty acids, up to 40 years before average age of diagnosis.

While neurotransmitters were discovered decades ago, evidence suggests that more transmitters are to be discovered using the presented approaches.

Analysis of conventional and gnotobiotic mice showed that a MHC-E-restricted unconventional CD8 T cell population is retained in the small intestine epithelium by a commensal bacterium.

A multidisciplinary approach sheds light on the fundamental mechanisms underlying social belief communication under uncertainty.

After an injury to the skin, murine wounds upregulate apoptosis and efferocytosis pathways, which are required for effective healing and may similarly impact wound healing in diabetic patients.

CFAP52 is a candidate for genetic diagnosing male infertility with defects of sperm head-tail connection and flagella development.

A regionally resolved single-cell RNA-sequencing analysis of GBM-associated leukocytes reveals distinct activation states of the main immune populations between tumor center, peripheral infiltration zone and blood.

A biochemical probe targeting Tregs shows the importance of Tregs for B cell homeostasis and peripheral B cell reduction is caused by an activated T-cell-dependent mechanism.