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    1. Chromosomes and Gene Expression
    2. Physics of Living Systems

    An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli

    Irina Kalita, Ira Alexandra Iosub ... Meriem El Karoui
    Single-molecule mRNA and protein quantification, combined with stochastic modelling, uncover a post-transcriptional regulatory mechanism that controls the expression of the extremely low-abundance DNA double-strand break repair enzyme RecBCD.
    1. Developmental Biology

    Redistribution of fragmented mitochondria ensures symmetric organelle partitioning and faithful chromosome segregation in mitotic mouse zygotes

    Haruna Gekko, Ruri Nomura ... Takuya Wakai
    Depletion of Dynamin-related protein 1, a key regulator of mitochondrial fission, in mouse zygotes impair symmetric organelle partitioning and chromosome segregation leading to early developmental arrest.
    1. Cell Biology

    Hexokinase regulates Mondo-mediated longevity via the PPP and organellar dynamics

    Raymond Laboy, Marjana Ndoci ... Adam Antebi
    Hexokinases regulate the metabolic transcription factor MML-1 via distinct pathways, linking glucose metabolism and organellar signaling to longevity control in Caenorhabditis elegans and mammals.
    1. Microbiology and Infectious Disease

    A biofilm-tropic Pseudomonas aeruginosa bacteriophage uses the exopolysaccharide Psl as receptor

    Brenna Walton, Serena Abbodante ... Arne Rietsch
    Certain bacteriophage are specifically adapted to infecting biofilm bacteria by exploiting biofilm characteristics, such as the exopolysaccharides produced by bacteria in biofilms.
    1. Evolutionary Biology

    Recurrent mutations drive the rapid evolution of pesticide resistance in the two-spotted spider mite Tetranychus urticae

    Li-Jun Cao, Jin-Cui Chen ... Shu-Jun Wei
    The rapid development of pesticide resistance in a mite across wide geographical areas is linked to the independent and repeated emergence of multiple mutations in target genes.
    1. Microbiology and Infectious Disease
    2. Structural Biology and Molecular Biophysics

    Navigating contradictions in enteric chemotactic stimuli

    Kailie Franco, Zealon Gentry-Lear ... Arden Baylink
    Motile Enterobacteriaceae override chemorepulsion from the microbiota metabolite indole in favor of nutrient attraction, challenging the idea that indole taxis protects the host against intestinal infection.
    1. Cancer Biology

    Human multiethnic radiogenomics reveals low-abundancy microRNA signature in plasma-derived extracellular vesicles for early diagnosis and molecular subtyping of pancreatic cancer

    Jianying Xu, Wenjie Shi ... Ulf Dietrich Kahlert
    A novel, non-invasive strategy combining radiomics and blood extracellular vesicle-derived microRNA profiling to sharpen pancreatic cancer diagnosis is introduced.
    1. Developmental Biology

    Long-term live imaging, cell identification and cell tracking in regenerating crustacean legs

    Çağrı Çevrim, Béryl Laplace-Builhé ... Michalis Averof
    Live imaging allows tracking cellular behaviours and cell fates during the entire course of leg regeneration, spanning approximately one week, in a crustacean model.
    1. Neuroscience

    Separable global and local beta burst dynamics in motor cortex of primates

    Preeya Khanna, Behraz Farrokhi ... Karunesh Ganguly
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology
    2. Neuroscience

    Cell-to-cell signalling mediated via CO2: activity dependent CO2 production in the axonal node opens Cx32 in the Schwann cell paranode

    Jack Butler, Lowell Mott ... Nicholas Dale
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid