Cell Biology

Latest articles

1. 1. Cell Biology

   SVEP1 enables efficient binding of angiopoietin-2 to the TIE1 receptor, allowing receptor phosphorylation and downstream signaling

   Katharina Uphoff, Melina Hußmann ... Dörte Schulte-Ostermann

   The interaction of important signaling pathway members identified through in silico and in vitro approaches provides a model that suggests local receptor multimerization through bridging functions of various ligands.
2. 1. Cancer Biology
   2. Cell Biology

   Molecular and functional analysis of calcium binding by a cancer-linked calreticulin mutant

   Ishmael Nii Ayibontey Tagoe, Amanpreet Kaur ... Malini Raghavan

   Endoplasmic reticulum and cytosolic calcium levels, and store-operated calcium entry, are comparable in calreticulin-deficient cells rescued with either wild-type calreticulin or the myeloproliferative neoplasm-linked Del52 mutant.
3. 1. Cell Biology
   2. Physiology

   Mechanosensory Physiology: Lymphatic vessels under pressure

   Asser F Bedair, Osama F Harraz

   Lymphatic vessels beat faster as they fill with fluid through a chain of calcium signaling, though the first pressure sensor remains a mystery.
4. 1. Cell Biology
   2. Neuroscience

   Parvalbumin interneuron ErbB4 controls ongoing network oscillations and olfactory behaviours in mice

   Bin Hu, Chi Geng ... Xiao-Yu Hou
5. 1. Cell Biology
   2. Physiology

   Primary cilia in the growing limb are preferentially orientated, uncoupled from centriolar position

   Theana Johnson, Swati Midha ... Angus KT Wann
6. 1. Cell Biology

   Pre-rRNA represses gene transcription in the XY body of male germ cells

   Linlin Chen, Xiaochen Gai ... Xiaochun Yu
7. 1. Cell Biology
   2. Stem Cells and Regenerative Medicine

   Spatial confinement induces oscillatory migration of epidermal keratinocytes and forms a three-compartment epithelial structure with epithelial–mesenchymal transition dynamics

   Takuma Nohara, Sota Itamoto ... Ken Natsuga
8. 1. Cell Biology

   A GCN1-independent activator of the kinase GCN2

   JiaYi Zhu, Giulia Emanuelli ... Stefan J Marciniak

   GCN2 can be pharmacologically activated independently of GCN1, revealing flexibility in the mechanisms governing kinase activation.
9. 1. Cell Biology

   Small brown planthopper infestation enhances it reproduction and insecticide tolerance by manipulating glucose distribution and levels in rice

   Hainan Zhang, Qi Zhang ... Jianjun Wang

   Small brown planthopper infestation drives rice glucose redistribution to boost its own reproduction and insecticide tolerance.
10. 1. Cell Biology

    p66Shc mediates SUMO2-induced endothelial dysfunction

    Jitendra Kumar, Shravan K Uppulapu ... Santosh Kumar

    SUMO2ylation of redox protein p66Shc drives endothelial dysfunction by promoting oxidative stress, identifying a potential therapeutic target for cardiovascular disease.