Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Developmental Biology

    Zinc is a key regulator of the sperm-specific K+ channel (Slo3) function

    Rizki Tsari Andriani, Tanadet Pipatpolkai ... Takafumi Kawai
    Intracellular zinc dynamically changes during sperm capacitation and regulates Slo3-mediated hyperpolarization, while directly inhibiting Slo3 currents through residues contributing to its slow dissociation.
    1. Cell Biology
    2. Neuroscience

    Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons

    Daniel Beaudet, Christopher L Berger, Adam G Hendricks
    Single-molecule motility assays and live-cell imaging in neurons reveal that tau hyperphosphorylation disrupts the formation of cooperative tau envelopes along microtubules and lysosomal transport.
    1. Cell Biology
    2. Immunology and Inflammation

    Digest before Ingest: Early Recruitment of Membrane-bound DNaseX to Phagocytic Cups in Macrophages

    Arghajit Pyne, Vivek Pandey ... Xuefeng Wang
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Physiology

    Ion channels and GPCR requirements for pressure-induced lymphatic chronotropy: Evidence for a Gαq/11-IP3R1-ANO1 pacemaking axis

    Michael J Davis, Hae Jin Kim ... Scott D Zawieja
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Genetics and Genomics

    Effects of knockdown of autophagy pathway genes on C. elegans longevity are highly condition dependent

    Kuei Ching Hsiung, Hannah Chapman ... David Gems
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology

    A Quartet of Native Orai Channel Isoforms Orchestrates Graded NFAT Activation and Transcription

    Ahmed Emam Abdelnaby, Yin-Hu Wang ... Mohamed Trebak
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    Molecular and Functional Analysis of Calcium Binding by a Cancer-linked Calreticulin Mutant

    Ishmael Nii Ayibontey Tagoe, Amanpreet Kaur ... Malini Raghavan
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Wound-induced syncytia outpace mononucleate neighbors during Drosophila wound repair

    James S White, Junmin Hua ... Andrea Page-McCaw
    In vivo live imaging, quantitative analysis, and computational modeling reveal that wound-induced epithelial cell fusion accelerates epithelial repair through several likely mechanisms.
    1. Cell Biology

    Winding-Up of Fibrin Fibers as a Novel Mechanism of Platelet-Mediated Fiber Compaction

    Alexei Grichine, Tatiana Kovalenko ... Karin Sadoul
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Incomplete
    • Solid
    1. Cell Biology
    2. Neuroscience

    Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly

    Katie X Dong, Yanbo Zhang ... Colleen N McLaughlin
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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Highlights

    1. Cell Biology
    2. Computational and Systems Biology
    Image credit: vividbiology.com

    The power of theory in the life sciences

    Jacob L Fine, Finn Creeggan ... Adam MR Groh
    1. Cell Biology
    Defeated wooden mannequin. Image credit: Marco Bianchetti (CC0)

    How to give cells an identity crisis

    Paige Dillon, Julie Hollien
    1. Cell Biology
    2. Developmental Biology
    Model of the heart. Image credit: Jesse Orrico (CC0)

    Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois

Senior editors

  1. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  2. Adèle L Marston
    University of Edinburgh, United Kingdom
  3. Dominique Soldati-Favre
    University of Geneva, Switzerland
  4. See more editors