Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)

    Constanza Salinas-Rebolledo, Javier Blesa ... Alejandro Rojas-Fernandez
    1. Cell Biology

    SMC5/6-mediated plasmid silencing is directed by SIMC1–SLF2 and antagonized by the SV40 large T antigen

    Martina Oravcová, Minghua Nie ... Michael N Boddy
    Distinct SMC5/6 subcomplexes mediate the transcriptional silencing of circular extrachromosomal DNA (SIMC1–SLF2) and repair of chromosomal DNA lesions (SLF1–SLF2), thus enabling exploration of SMC5/6 functions in innate immunity and cancer.
    1. Cell Biology

    The RAB27A effector SYTL5 regulates mitophagy and mitochondrial metabolism

    Ana Lapão, Lauren Sophie Johnson ... Anne Simonsen
    RAB27A-dependent mitochondrial recruitment of SYTL5 promotes mitophagy and mitochondrial bioenergetics upon hypoxia.
    1. Cell Biology

    Human dynein-dynactin is a fast processive motor in living cells

    Vikash Verma, Patricia Wadsworth, Thomas J Maresca
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    ATP-independent phosphate recycling on AGC kinase activation loops induced by alkali metal ions

    Koji Kubouchi, Hideyuki Mukai
    Not revised
    Reviewed Preprint v1
    • Incomplete
    1. Cell Biology

    Overexpression of Ssd1 and calorie restriction extend yeast replicative lifespan by preventing deleterious age-dependent iron uptake

    J Ignacio Gutierrez, Claudia Edgar, Jessica K Tyler
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Immunology and Inflammation

    Extracellular matrices regulate extravasation journey of leukocytes and inflammatory tissue fate

    Yu-Tung Li
    Revised
    Reviewed Preprint v2
    Updated
    1. Cell Biology
    2. Neuroscience

    Endosome-associated Rab GTPases control distinct aspects of neural circuit assembly

    Katherine X Dong, Hui Ji ... Colleen N McLaughlin
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    A systematic bi-genomic split-GFP assay illuminates the mitochondrial matrix proteome and protein targeting routes

    Yury S Bykov, Solène Zuttion ... Maya Schuldiner
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology

    WNKs regulate mouse behavior and alter central nervous system glucose uptake and insulin signaling

    Ankita B Jaykumar, Derk Binns ... Melanie H Cobb
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
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Highlights

    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Controlling cell size

    Angela Montero, Lydia WS Finley
    1. Cell Biology
    2. Chromosomes and Gene Expression

    A crossroads in the aging process

    Kiyan Shabestary, Daniel E Gottschling
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology
    3. Biochemistry and Chemical Biology

    Allosteric Regulation of Kinase Activity – call for papers

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Jürgen Kleine-Vehn
    University of Freiburg, Germany
  3. Dominique Soldati-Favre
    University of Geneva, Switzerland
  4. See more editors