Cell Biology

Latest articles

1. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   A biochemical mechanism for Stu2/XMAP215-family microtubule polymerases

   Binnu Gangadharan, Daniel L Kober, Luke M Rice

   Evolutionarily unrelated microtubule and actin regulatory factors use the same mechanism to accelerate polymerization.
2. 1. Cell Biology

   A high-throughput assay for the measurement of Ca²⁺-oscillations and insulin release from uniformly sized β-cell spheroids

   Stijn Robben, Patricia Davidson ... Thomas Voets
3. 1. Cell Biology

   Cardiolipin deficiency disrupts electron transport chain and drives steatohepatitis

   Marisa J Brothwell, Guoshen Cao ... Katsuhiko Funai

   Metabolic dysfunction-associated steatotic liver disease is associated with reduced mitochondrial cardiolipin concentration in mice and humans, and cardiolipin deficiency was sufficient to drive steatosis and fibrosis in the liver.
4. 1. Cell Biology

   Xkr regulates phosphatidylserine transport via ER-PM contact sites to promote apoptotic cell clearance

   Qian Zheng, Xinyu Ma ... Hui Xiao
5. 1. Cell Biology

   MARBL: A Live-Cell Method for Profiling Bioenergetic Heterogeneity by Noncanonical Methionine Labeling of the Cell Surface Proteome

   Lillian R Delacruz, Ming Ye ... Alison E Ringel
6. 1. Cell Biology

   Functional High Throughput Drug Screening Reveals Cyproheptadine as a Novel Treatment for LMNA-related Cardiomyopathy

   Hananeh Fonoudi, Ali Negahi Shirazi ... Paul W Burridge
7. 1. Cell Biology
   2. Neuroscience

   Tau hyperphosphorylation impairs cooperative binding to microtubules and perturbs organelle trafficking in neurons

   Daniel Beaudet, Christopher L Berger, Adam G Hendricks
8. 1. Cell Biology

   SETD6-mediated methylation of PPARγ establishes a transcriptional feedback circuit promoting lipid accumulation in liver-derived cells

   Noa Nashnaz, Dana Goldberg ... Dan Levy

   SETD6-mediated methylation of PPARγ establishes a positive feedback mechanism that enhances transcriptional activation and promotes hepatic lipid accumulation.
9. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Tracking maternal proteins uncovers a central role for the residual body in organelle recycling during Toxoplasma gondii replication

   Julia von Knoerzer-Suckow, Parnian Sazegar ... Markus Meissner
10. 1. Cell Biology

    Zasp52’s differentially expressed intrinsically disordered region confers thin filament stability at the Z-disc

    Nikolai Ho, Frieder Schöck

    The Z-disc of muscle sarcomeres is a solid aggregate stabilized by the intrinsically disordered region of the Alp/Enigma family protein Zasp52.