Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    p66Shc Mediates SUMO2-induced Endothelial Dysfunction

    Jitendra Kumar, Shravan K Uppulapu ... Santosh Kumar
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Compelling
    • Solid
    1. Cell Biology

    Sequential adaptor function of Treacle and MDC1 couples nucleolar reorganization to RNF8-dependent recruitment of HDR factors

    Andrea Haenel, Johannes Leyrer ... Manuel Stucki
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Convincing
    1. Cell Biology

    SETD6-mediated methylation of PPARγ establishes a transcriptional feedback circuit promoting lipid accumulation in liver-derived cells

    Noa Nashnaz, Dana Goldberg ... Dan Levy
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Centrosome Migration and Apical Membrane Formation in Polarized Epithelial Cells: Insights from the MDCK Cyst Model

    Po-Kai Wang, Keng-Hui Lin, Tang K Tang
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Cancer Biology

    Slap restricts oncogenic Src-family kinase signaling to maintain colonic epithelial homeostasis

    Dana Naim, Zouheir Houhou ... Serge Roche
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Cell Biology
    2. Neuroscience

    Engulfment by brain macrophages in a short-lived vertebrate

    Rahul Nagvekar, Angela N Pogson ... Anne Brunet
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology

    Analysis of cancer mutations introduced into the Drosophila melanogaster Notch negative regulatory region uncovers a diversity of regulatory outcomes

    Hideyuki Shimizu, Martin Baron
    Heterogeneity in outcomes of differently located activating mutations of Notch indicates the need and potential for mutant specific targeting of Notch in cancer.
    1. Cell Biology
    2. Cancer Biology

    RAB14-dependent tubulovesicular recycling directs MET to invadopodia, promoting TNBC cell invasion

    Amrita Khamari, Atreyee Guria ... Sunando Datta
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Cell Biology
    2. Developmental Biology

    Organ Development: Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois
    A novel computational pipeline reveals patterns of tissue movement and growth in early heart formation and advances virtual modeling of development.
    Version of Record
    Insight
    1. Cell Biology

    Decoupling AMPK from fatty acid synthesis allows maintenance of fitness late in life

    Hanane Hadj-Moussa, Megan Ulusan ... Jonathan Houseley
    Re-engineering a highly conserved metabolic pathway in yeast prevents age-related functional decline and proves that ageing is not inevitably linked to loss of fitness.
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Highlights

    1. Cell Biology
    2. Developmental Biology
    Model of the heart. Image credit: Jesse Orrico (CC0)

    Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois
    1. Cell Biology
    2. Neuroscience

    The role of lipids in hearing

    Yein Christina Park, Angela Ballesteros
    1. Cancer Biology
    2. Cell Biology

    Chemotherapy: Lipid balance and chemoresistance in cancer cells

    Kaori Kanemaru, Yoshikazu Nakamura

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  4. See more editors