Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response

    Akinori Endo, Chikage Takahashi ... Yukiko Yoshida
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Deletion of sulfate transporter SUL1 extends yeast replicative lifespan via reduced PKA signaling instead of decreased sulfate uptake

    Juan Long, Meng Ma ... Jing Yang
    SUL1 deletion extends lifespan via PKA-MSN2 pathways, underscoring nutrient signaling over sulfate transport in aging regulation.
    1. Cell Biology
    2. Immunology and Inflammation

    β-glucan reprograms macrophages to attenuate efferocytosis of cancer cells

    Alexandros Chatzis, Jakub Lukaszonek ... Ioannis Kourtzelis
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Developmental Biology

    Sulfation affects apical extracellular matrix organization during development of the Drosophila embryonic salivary gland tube

    J Luke Woodward, Jeffrey Matthew ... SeYeon Chung
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche

    Claire Masson, Cyril Scandola ... Anita Eckly
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Compelling
    1. Cell Biology

    Membrane potential modulates ERK activity and cell proliferation

    Mari Sasaki, Masanobu Nakahara ... Fumihito Ono
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Compelling
    • Incomplete
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Dock-and-lock binding of SxIP ligands is required for stable and selective EB1 interactions

    Teresa Almeida, Eleanor Hargreaves ... Igor Barsukov
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology

    C-terminal tagging, transmembrane domain hydrophobicity, and an ER retention motif influence the secretory trafficking of the inner nuclear membrane protein emerin

    Jessica Mella, Regan F Volk ... Abigail Buchwalter
    The inner nuclear membrane protein emerin readily traffics through the secretory pathway via its hydrophobic transmembrane domain when tagged with C-terminal GFP.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Enalapril mitigates senescence and aging-related phenotypes in human cells and mice via pSmad1/5/9-driven antioxidative genes

    Wencong Lyu, Haochen Wang ... Wei Tao
    Enalapril combats the effects of senescence by activating the pSmad1/5/9–antioxidative gene axis, enhancing antioxidative defenses and promoting cell proliferation, thereby supporting healthy aging.

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors