Cell Biology

Latest articles

1. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Chromosomes: Exploring a crossroads in the aging process

   Kiyan Shabestary, Daniel E Gottschling

   Experiments on yeast show that the nuclear pore complex has a central role in the loss of chromosomes associated with aging.
2. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Dissociation of the nuclear basket triggers chromosome loss in aging yeast

   Mihailo Mirkovic, Jordan McCarthy ... Yves Barral

   Aging results in remodeling of the nuclear pore complex and leakage of intron-containing pre-mRNA out of the nucleus, altering gene function and mitotic stability of old cells.
3. 1. Cell Biology

   Deep3DSIM: Super-resolution imaging of thick tissue using 3D structured illumination with adaptive optics

   Jingyu Wang, Danail Stoychev ... Ilan Davis

   Deep3DSIM enables super-resolution imaging >130 µm into complex tissues of fixed and live specimens in an upright configuration, allowing sample manipulation, as well as rapid refocusing without the need to move the specimen or objective lens.
4. 1. Cell Biology

   The Rab7-Epg5 and Rab39-ema modules cooperatively position autophagosomes for efficient lysosomal fusions

   Attila Boda, Villő Balázs ... Péter Lőrincz

   An RNAi based genetic screen and subsequent analyses reveal how dyneins and small GTPases coordinate autophagosome positioning at the ncMTOC in fat cells, advancing understanding of autophagic vesicle transport.
5. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Cell membrane glycan contents are biochemical factors that constitute a kinetic barrier to viral particle uptake in a protein-nonspecific manner

   Yoshihisa Kaizuka, Rika Machida

   Intermolecular steric repulsion generated by glycans on the cell membrane inhibits viral infection by preventing the formation of a virus-cell interface, regardless of the identity of molecules for glycan modification.
6. 1. Cell Biology

   Dominant spinal muscular atrophy linked mutations in the cargo binding domain of BICD2 result in altered interactomes and dynein hyperactivity

   Hannah Neiswender, Jessica E Pride ... Graydon B Gonsalvez
7. 1. Cell Biology

   Suppression of interferon signaling via small molecule modulation of TFAM

   Dionisia P Sideris, Hsuan Lee ... Lin Lyu
8. 1. Cell Biology

   Cohesin reconstitution and homologous recombination repair of DNA double strand breaks in late mitosis

   Jessel Ayra-Plasencia, Sara Medina-Suárez ... Félix Machín
9. 1. Cell Biology
   2. Developmental Biology

   BICC1 Interacts with PKD1 and PKD2 to Drive Cystogenesis in ADPKD

   Uyen Tran, Andrew J Streets ... Oliver Wessely
10. 1. Cell Biology
    2. Computational and Systems Biology

    Extrusion-modulated DnaA activity oscillations coordinate DNA replication with biomass growth

    Dengjin Li, Hai Zheng ... Chenli Liu