Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology

    Engineering ATP import in yeast uncovers a synthetic route to extend cellular lifespan

    Naci Oz, Hetian Su ... Alaattin Kaya
    Directly manipulating cellular energy levels suppresses catabolic pathways and enhances mitochondrial maintenance, establishing bioenergetic homeostasis as a fundamental driver of cellular longevity.
    1. Cell Biology

    SPEx: Compartment-Resolved Proteomics via Expansion Microscopy–Guided Microdissection

    Curdin A Franziscus, Alexia Ferrand ... Anne Spang
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Cell Biology
    2. Neuroscience

    ATP8B1–TMEM30B Flippase Activity Maintains Stereocilia Lipid Asymmetry Required for Hearing

    Henry N De Hoyos, Sihan Li ... Jung-Bum Shin
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Chromosomes and Gene Expression

    The nuclear membrane protein Samp1 links peripheral genome organization to the myogenic transcriptional program

    Urška Kašnik, Irene Mei ... Einar Hallberg
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    • Incomplete
    1. Cell Biology
    2. Developmental Biology

    Dynamin 2–dependent endocytosis differentially regulates ligand and receptor contributions to Notch signaling during neural precursor cell fate determination

    Joshua J Breunig, Jon I Arellano ... Pasko Rakic
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Integrin-dependent trafficking of CD98hc reduces endocytic noise to maintain metabolic homeostasis

    F Sila Rizalar, Hans Peter Grimm ... Roberto Villaseñor
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Spatial confinement induces oscillatory migration of epidermal keratinocytes and forms a three-compartment epithelial structure with epithelial–mesenchymal transition dynamics

    Takuma Nohara, Sota Itamoto ... Ken Natsuga
    Skin cells can preserve the original epithelium while forming a new one beneath 3 µm pores, with passage dependent on actin polymerization and restrained by Piezo1 and keratin 6.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Kinesin-1 holoenzyme assembly coordinates cargo-adaptor recognition with heavy-chain autoinhibition

    Jingling Niu, Mengmeng Zhang ... Chao Wang
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Neuroscience

    Neuropeptides NLP-10 and FLP-18 stimulate lipid catabolism in chronically diet-restricted Caenorhabditis elegans

    Jiaming Liu, Liyun Lin ... Jintao Luo
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Cell Biology
    2. Physics of Living Systems

    Collective directional memory controls the range of epithelial cell migration

    Helena Canever, Hugo Lachuer ... Nicolas Borghi
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
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Highlights

    1. Cell Biology
    2. Physiology
    Checking the blood pressure. Image credit: Julia Taubitz (CC0)

    Under pressure

    Asser F Bedair, Osama F Harraz
    1. Cell Biology
    2. Computational and Systems Biology
    Image credit: vividbiology.com

    The power of theory in the life sciences

    Jacob L Fine, Finn Creeggan ... Adam MR Groh
    1. Cell Biology
    Defeated wooden mannequin. Image credit: Marco Bianchetti (CC0)

    How to give cells an identity crisis

    Paige Dillon, Julie Hollien

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Felix Campelo
    Pompeu Fabra University, Spain
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors