Developmental Biology

Developmental Biology

eLife reviews research in areas including cell migration, proliferation and differentiation, and inductive and signaling interactions. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells

    Justine Bajohr, Erica Y Scott ... Maryam Faiz
    Revised
    Reviewed Preprint v3
    Updated
    • Useful
    • Convincing
    1. Developmental Biology

    Bidirectional redistribution of actomyosin drives epithelial invagination in ascidian siphon tube morphogenesis

    Jinghan Qiao, Pengyu Yu ... Bo Dong
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Ectopic hAMH-driven SOX17 expression induces hyperplastic Sertoli valve formation in mouse testes

    Xiao Han, Aya Uchida ... Yoshiakira Kanai
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology
    2. Microbiology and Infectious Disease

    In vitro sexual dimorphism establishment in schistosomes

    Rémi Pichon, Magda E Lotkowska ... Gabriel Rinaldi
    Establishment of sexually dimorphic schistosomes entirely in vitro from mechanically transformed cercariae paves the way for uncovering the cellular and molecular cues underlying development, providing potential targets for novel control strategies.
    1. Developmental Biology

    Genome-wide discovery of cis-regulatory elements in a large genome

    Gillian Forbes, Emilia Skafida ... Mathilde Paris
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Developmental Biology

    Primordial cardiomyocytes orchestrate myocardial morphogenesis and vascularization but are dispensable for regeneration

    Jisheng Sun, Lu Chen, Jinhu Wang
    Primordial cardiomyocytes play an essential role in myocardial morphogenesis and coronary vascularization, but not in adult zebrafish heart regeneration.
    1. Developmental Biology

    Cellular basis of accelerated whole-tooth regeneration

    Talha Mubeen, Haowen He ... Jeffrey T Streelman
    Revised
    Reviewed Preprint v2
    Updated
    • Valuable
    • Solid
    1. Developmental Biology

    Trpv4 links environmental temperature to testicular differentiation in hermaphroditic ricefield eel

    Zhi Yang, Tingting Luo ... Yuhua Sun
    Warm temperature promotes gonadal transformation of ricefield eel by inducing the expression of male pathway genes in ovaries via the Trpv4-pStat3-Kdm6b-Dmrt1 axis.
    1. Developmental Biology
    2. Neuroscience

    Complementary vertebrate Wac models exhibit phenotypes relevant to DeSanto-Shinawi Syndrome

    Kang-Han Lee, April M Stafford ... Daniel Vogt
    Two distinct vertebrate models were generated and phenotyped to study DESSH syndrome caused by the Wac gene.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Nutrient Microenvironments Reprogram Pigment Epithelium Metabolism and Phenotype

    Rayne R Lim, Emily Zhao ... Jennifer R Chao
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
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Highlights

    1. Cell Biology
    2. Developmental Biology
    Model of the heart. Image credit: Jesse Orrico (CC0)

    Following your heart as it takes shape

    Alexandra Trouilloud, Nicole C Dubois
    1. Developmental Biology

    Oocyte Development: The discovery of the mammalian fusome

    Michael Buszczak, Anirban Dasgupta
    1. Developmental Biology
    2. Genetics and Genomics

    Written out of history

    Lisa M Thomann, Julie Batut

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Albert Cardona
    University of Cambridge, United Kingdom
  3. Jürgen Kleine-Vehn
    University of Freiburg, Germany
  4. See more editors