Chromosomes and Gene Expression

Latest articles

1. 1. Cancer Biology
   2. Chromosomes and Gene Expression

   Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II

   Raphael Vidal, Eoin Leen ... Gabriele Büchel

   MYCN and TFIIIC exert a censoring function during early transcription, limiting the accumulation of inactive RNAPII at the promoter and facilitating promoter-proximal degradation of nascent RNA.
2. 1. Chromosomes and Gene Expression
   2. Medicine

   LncRNA Snhg3 Aggravates Hepatic Steatosis via PPARγ Signaling

   Xianghong Xie, Mingyue Gao ... Xiaojun Liu
3. 1. Chromosomes and Gene Expression

   Target-specific requirements for RNA interference can arise through restricted RNA amplification despite the lack of specialized pathways

   Daphne R Knudsen-Palmer, Pravrutha Raman ... Antony M Jose

   Experimental results and computational modeling reveal many factors that influence if a gene can be efficiently silenced using RNA interference.
4. 1. Chromosomes and Gene Expression

   Artificially inserted strong promoter containing multiple G-quadruplexes induces long-range chromatin modification

   Shuvra Shekhar Roy, Sulochana Bagri ... Shantanu Chowdhury

   Non-duplex DNA structures induce distant chromatin-chromatin interactions and gene activation over long distances.
5. 1. Chromosomes and Gene Expression

   A comparative study of the cryo-EM structures of S. cerevisiae and human anaphase-promoting complex/cyclosome (APC/C)

   Ester Vazquez-Fernandez, Jing Yang ... David Barford
6. 1. Chromosomes and Gene Expression
   2. Immunology and Inflammation

   Dynamic chromatin architecture identifies new autoimmune-associated enhancers for IL2 and novel genes regulating CD4+ T cell activation

   Matthew C Pahl, Prabhat Sharma ... Andrew D Wells
7. 1. Chromosomes and Gene Expression
   2. Structural Biology and Molecular Biophysics

   OpenNucleome for high-resolution nuclear structural and dynamical modeling

   Zhuohan Lao, Kartik D Kamat ... Bin Zhang

   An open-source tool for computational simulations of the human genome has been introduced, enabling the characterization of complex nuclear environments and the interpretation of experimental observations.
8. 1. Chromosomes and Gene Expression

   Transcriptional inhibition after irradiation occurs preferentially at highly expressed genes in a manner dependent on cell cycle progression

   Zulong Chen, Xin Wang ... Jessica Tyler
9. 1. Biochemistry and Chemical Biology
   2. Chromosomes and Gene Expression

   Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome

   Kira Cozzolino, Lynn Sanford ... Dylan J Taatjes
10. 1. Chromosomes and Gene Expression

    An anciently diverged family of RNA binding proteins maintain correct splicing of a class of ultra-long exons through cryptic splice site repression

    Chileleko Siachisumo, Sara Luzzi ... David J Elliott