Chromosomes and Gene Expression

Chromosomes and Gene Expression

eLife reviews research ranging from transcription and RNA processing to epigenetics and chromatin biology. Learn more about what we review and sign up for the latest research.
Illustration by Davide Bonazzi

Latest articles

    1. Chromosomes and Gene Expression

    Epigenetics: Linking environmental factors and gene regulation

    Signe Penner-Goeke, Elisabeth B Binder
    A technique called mSTARR-seq sheds light on how DNA methylation may shape responses to external stimuli by altering the activity of sequences that control gene expression.
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    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Dynamic 1D search and processive nucleosome translocations by RSC and ISW2 chromatin remodelers

    Jee Min Kim, Claudia C Carcamo ... Carl Wu
    Single-particle imaging of RSC and ISW2 chromatin remodelers on DNA stretched between dual optical tweezers reveals distinctive 1D diffusion and opposing push–pull nucleosome translocation on engagement with sparse nucleosome arrays.
    1. Chromosomes and Gene Expression
    2. Structural Biology and Molecular Biophysics

    Chromatin Remodeling: The voyage is as important as the harbor

    Anton Sabantsev, Sebastian Deindl
    To find nucleosomes, chromatin remodelers slide and hop along DNA, and their direction of approach affects the direction that nucleosomes slide in.
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    1. Cell Biology
    2. Chromosomes and Gene Expression

    Heat stress impairs centromere structure and segregation of meiotic chromosomes in Arabidopsis

    Lucie Crhak Khaitova, Pavlina Mikulkova ... Karel Riha
    1. Chromosomes and Gene Expression
    2. Neuroscience

    Inhibition of Cpeb3 ribozyme elevates CPEB3 protein expression and polyadenylation of its target mRNAs and enhances object location memory

    Claire C Chen, Joseph Han ... Andrej Luptak
    The mammalian CPEB3 self-cleaving ribozyme modulates expression of the CPEB3 mRNA and protein, altering translation of plasticity-related proteins and hippocampus-dependent memory.

Senior editors

  1. Yamini Dalal
    National Cancer Institute, United States
  2. Lori Sussel
    University of Colorado Anschutz Medical Campus, United States
  3. K VijayRaghavan
    K VijayRaghavan
    National Centre for Biological Sciences, Tata Institute of Fundamental Research, India
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