Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
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Latest articles

    1. Genetics and Genomics
    2. Microbiology and Infectious Disease

    Neisseria gonorrhoeae LIN codes: a Robust, Multi-Resolution Lineage Nomenclature

    Anastasia Unitt, Made Krisna ... Odile B Harrison
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Compelling
    1. Genetics and Genomics

    Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome

    Tanja Nielsen, Anaïs Kervadec ... Alexandre R Colas
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    High-throughput development and characterization of new functional nanobodies for gene regulation and epigenetic control in human cells

    Jun Wan, Abby R Thurm ... Lacramioara Bintu
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Genetics and Genomics
    2. Neuroscience

    Avoidance of hydrogen sulfide is modulated by external and internal states in Caenorhabditis elegans

    Longjun Pu, Lina Zhao ... Changchun Chen
    Mitochondrial remodeling, ROS-dependent signaling, and diverse environmental and physiological cues underlie the initiation and persistence of locomotory activity of C. elegans in toxic H2S.
    1. Genetics and Genomics

    Non-visual light modulates behavioral memory and gene expression in C. elegans

    Zhijian Ji, Bingying Wang ... Dengke K Ma
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Genetics and Genomics

    CNN-based learning of single-cell transcriptomes reveals a blood-detectable multi-cancer signature of brain metastasis

    Ryan Lusby, Debojyoti Chowdhury ... Vijay K Tiwari
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics
    2. Evolutionary Biology

    Lifestyles shape genome size and gene content in fungal pathogens

    Anna Fijarczyk, Pauline Hessenauer ... Christian R Landry
    Revised
    Reviewed Preprint v3
    Updated
    • Important
    • Solid
    1. Genetics and Genomics

    Genomic privacy risks in GWAS summary statistics

    Ao Lan, Yudi Pawitan, Xia Shen
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics

    Phenotypic impact of individual conserved neuronal microexons and their master regulators in zebrafish

    Laura Lopez-Blanch, Cristina Rodríguez-Marin ... Manuel Irimia
    A multi-level assessment of the relevance of 18 highly conserved neural zebrafish microexons showed that individual deletions of most microexons did not exhibit strong phenotypes, likely because of compensatory changes.
    1. Genetics and Genomics
    2. Computational and Systems Biology

    JAX Animal Behavior System (JABS): A genetics informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse

    Anshul Choudhary, Brian Q Geuther ... Vivek Kumar
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
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Highlights

    1. Genetics and Genomics

    Epigenetic inheritance in C. elegans

    Lesley T MacNeil
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology
    3. Genetics and Genomics

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    1. Genetics and Genomics
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Senior editors

  1. Murim Choi
    Seoul National University College of Medicine, South Korea
  2. Yamini Dalal
    National Cancer Institute, United States
  3. Alan Moses
    University of Toronto, Canada
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