Genetics and Genomics

Latest articles

1. 1. Cell Biology
   2. Genetics and Genomics

   Impact of Maximal Overexpression of a Non-toxic Protein on Yeast Cell Physiology

   Yuri Fujita, Shotaro Namba, Hisao Moriya
2. 1. Developmental Biology
   2. Genetics and Genomics

   The role of heterochronic gene expression and regulatory architecture in early developmental divergence

   Nathan D. Harry, Christina Zakas
3. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   A single-cell atlas of the miracidium larva of the human blood fluke Schistosoma mansoni: cell types, developmental pathways and tissue architecture

   Teresa Attenborough, Kate A Rawlinson ... Matthew Berriman
4. 1. Genetics and Genomics
   2. Microbiology and Infectious Disease

   Non-cognate immunity proteins provide broader defenses against interbacterial effectors in microbial communities

   Abigail Knecht, Denise Sirias ... Karine A Gibbs
5. 1. Biochemistry and Chemical Biology
   2. Genetics and Genomics

   Genome-wide mapping of native co-localized G4s and R-loops in living cells

   Ting Liu, Xing Shen ... Zhihong Xue
6. 1. Genetics and Genomics
   2. Stem Cells and Regenerative Medicine

   Delivery of A Jagged1-PEG-MAL hydrogel with Pediatric Human Bone Cells Regenerates Critically-Sized Craniofacial Bone Defects

   Archana Kamalakar, Brendan Tobin ... Steven L Goudy
7. 1. Genetics and Genomics

   Deficiency of IQCH causes male infertility in humans and mice

   Tiechao Ruan, Ruixi Zhou ... Ying Shen

   IQCH is required for acrosome and axoneme development during spermatogenesis in humans and mice.
8. 1. Genetics and Genomics

   Tradeoffs in Modeling Context Dependency in Complex Trait Genetics

   Eric Weine, Samuel Pattillo Smith ... Arbel Harpak
9. 1. Genetics and Genomics
   2. Epidemiology and Global Health

   Maternal smoking DNA methylation risk score associated with health outcomes in offspring of European and South Asian ancestry

   Wei Q Deng, Nathan Cawte ... Sonia S Anand
10. 1. Computational and Systems Biology
    2. Genetics and Genomics

    Discovery of runs-of-homozygosity diplotype clusters and their associations with diseases in UK Biobank

    Ardalan Naseri, Degui Zhi, Shaojie Zhang

    ROH-DICE is an efficient method for detecting ROH clusters in biobank data, enabling the study of population history of large cohorts, and providing a new genome-wide association analysis approach for finding disease-causing loci with multi-marker recessive effects.