Genetics and Genomics

Genetics and Genomics

eLife reviews research including the genetic basis of health and disease, epigenetics, genomics, medical genetics, genetic epidemiology, and population genetics. Learn more about what we review and sign up for the latest research.
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Latest articles

    1. Genetics and Genomics
    2. Computational and Systems Biology

    JAX Animal Behavior System (JABS): A genetics informed, end-to-end advanced behavioral phenotyping platform for the laboratory mouse

    Anshul Choudhary, Brian Q Geuther ... Vivek Kumar
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Acute opioid responses are modulated by dynamic interactions of Oprm1 and Fgf12

    Paige M Lemen, Yanning Zuo ... Hao Chen
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Compelling
    1. Genetics and Genomics

    Independent validation of transgenerational inheritance of learned pathogen avoidance in Caenorhabditis elegans

    Aalimah Akinosho, Joseph Alexander ... Andres Gabriel Vidal-Gadea
    Independent replication confirms that avoidance of pathogenic PA14 learned by Caenorhabditis elegans persists through the F2 generation using standardized sodium azide immobilization choice assays, clarifying prior reproducibility concerns.
    1. Genetics and Genomics

    Transgenerational Epigenetic Inheritance: Twists and turns in the story of learned avoidance

    Lesley T MacNeil
    Evidence that learned avoidance of a pathogenic bacterium can be transmitted to future generations in C. elegans is growing.
    Version of Record
    Insight
    1. Genetics and Genomics
    2. Ecology

    Microbial consortia in salt marsh sediments are sequentially buried over millennia and genomic complementarity analysis indicates an important role in complex carbon decomposition

    Joseph H Vineis, Ashley N Bulseco ... Jennifer L Bowen
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Incomplete
    1. Developmental Biology
    2. Genetics and Genomics

    HoxB-derived hoxba and hoxbb clusters are essential for the anterior-posterior positioning of zebrafish pectoral fins

    Morimichi Kikuchi, Renka Fujii ... Akinori Kawamura
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Genetics and Genomics

    Mutational and Expression Profile of ZNF217, ZNF750, ZNF703 Zinc Finger Genes in Kenya Women diagnosed with Breast Cancer

    Michael Kitoi, John Gitau ... Francis Makokha
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Genetics and Genomics

    Redox Dyshomeostasis Links Renal and Neuronal Dysfunction in Drosophila Models of Gaucher and Parkinson’s Disease

    Alexander J Hull, Magda L Atilano, Kerri J Kinghorn
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Cell Biology
    2. Genetics and Genomics

    Mechanistic insights into transcriptional regulation of ARHGAP36 expression identify a factor predictive of neuroblastoma survival

    Serhiy Havrylov, Armin M Gamper, Ordan J Lehmann
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Genetics and Genomics

    Monocyte-endothelial interactions as a targetable node in clonal hematopoiesis-mediated cardiovascular disease

    Alyssa C Parker, J Brett Heimlich ... Alexander G Bick
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
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Highlights

    1. Genetics and Genomics

    Epigenetic inheritance in C. elegans

    Lesley T MacNeil
    1. Genetics and Genomics
    2. Neuroscience

    How stress can extend lifespan

    Loren Cocciolone, Valeria Uvarova, Patricija van Oosten-Hawle
    1. Biochemistry and Chemical Biology
    2. Computational and Systems Biology
    3. Genetics and Genomics

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Senior editors

  1. Murim Choi
    Seoul National University College of Medicine, South Korea
  2. Yamini Dalal
    National Cancer Institute, United States
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors