Genetics and Genomics

Latest articles

1. 1. Evolutionary Biology
   2. Genetics and Genomics

   G-protein-coupled receptor diversity and evolution in the closest living relatives of metazoa

   Alain Garcia De Las Bayonas, Nicole King

   Up-to-date computational pipeline characterizes G-protein-coupled receptor (GPCR) repertoires in the closest relatives of metazoans, providing a framework to investigate the evolutionary origins and ancestral functions of key metazoan signaling pathways.
2. 1. Evolutionary Biology
   2. Genetics and Genomics

   Lifestyles shape genome size and gene content in fungal pathogens

   Anna Fijarczyk, Pauline Hessenauer ... Christian R Landry

   A genomic analysis shows that the evolution of genome size and gene content among fungal pathogens in the class Sordariomycetes varies depending on their interactions with hosts and vectors.
3. 1. Genetics and Genomics

   Competition for the conserved branch point sequence influences physiological outcomes in pre-mRNA splicing

   Karen Larissa Pereira de Castro, Jose M Abril ... W Samuel Fagg
4. 1. Genetics and Genomics

   Chromatin accessibility variation provides insights into missing regulation underlying immune-mediated diseases

   Raehoon Jeong, Martha L Bulyk

   Analyzing population-level chromatin accessibility data shows added benefit over utilizing only gene expression data in elucidating the genetic mechanism of disease-associated variants.
5. 1. Cell Biology
   2. Genetics and Genomics

   Heme’s relevance genuine? Re-visiting the roles of TANGO2 homologs including HRG-9 and HRG-10 in C. elegans

   Sarah E Sandkuhler, Kayla S Youngs ... Samuel J Mackenzie
6. 1. Genetics and Genomics
   2. Neuroscience

   Impaired excitability of fast-spiking neurons in a novel mouse model of KCNC1 epileptic encephalopathy

   Eric R Wengert, Sophie R Liebergall ... Ethan M Goldberg
7. 1. Genetics and Genomics
   2. Cancer Biology

   Early Diagnosis and Prognostic Prediction of Colorectal Cancer through Plasma Methylation Regions

   Lingqin Zhu, Lang Yang ... Jianqiu Sheng
8. 1. Chromosomes and Gene Expression
   2. Genetics and Genomics

   Defining the chromatin-associated protein landscapes on Trypanosoma brucei repetitive elements using synthetic TALE proteins

   Roberta Carloni, Tadhg Devlin ... Robin C Allshire
9. 1. Genetics and Genomics

   Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome

   Tanja Nielsen, Anaïs Kervadec ... Alexandre R Colas

   Cross-species functional genomics identify ribosomal protein genes as key regulators of cardiomyocyte proliferation and heart development, implicating them as candidate modifiers for HLHS and revealing new avenues for therapeutic discovery.
10. 1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Role of ADMA-histones in dual-strand piRNA source loci recognition by Rhino

    Raku Saito, Hirotsugu Ishizu ... Mikiko C Siomi