Research Articles published by eLife are full-length studies that present important breakthroughs across the life sciences and biomedicine. There is no maximum length and no limits on the number of display items.
PITAR interaction with TRIM28 mRNA, which encodes a p53 targeting E3 ubiquitin ligase, keeps p53 levels low for cancer cells to divide and attenuates the DNA damage response by p53.
Luis Alberto Bezares Calderón, Réza Shahidi, Gáspár Jékely
Ciliated zooplankton larvae sense pressure by ciliary photoreceptor cells, which increase the beating of locomotor cilia via a serotonergic motor circuit leading to rapid upward swimming during barotaxis.
Frederick Federer, Justin Balsor ... Alessandra Angelucci
The gene-regulatory enhancers h56D and S5E2 restrict transgene expression to GABAergic and parvalbumin-positive interneurons, respectively, across marmoset cortical layers, thus representing a promising tool for circuit dissection in non-human primates.
The male-specific tumor-suppressive effects of minor p53 isoforms were correlated with higher Ackr4 expression levels, which have implications for sex-specific cancer prognosis in humans.
Many well-studied maternal developmental pathways that are required for embryonic development in Drosophila are regulated by the transcription factor OVO in the Drosophila female germline.
Behavioral studies reveal that bumblebees distinguish between continuous and interrupted strings by using a combination of image matching and associative learning.
