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    1. Computational and Systems Biology
    2. Medicine

    Early warning system forecasts who needs critical care for COVID-19

    An algorithm can accurately predict which hospitalised patients are at the highest risk of death and require critical care, regardless of immune protection status and virus variant.
    1. Medicine
    2. Neuroscience

    Concussion symptoms in children may have multiple underlying causes

    A study suggests there are multiple ways that brain damage caused by paediatric concussions can lead to different sets of symptoms, and this complexity can be missed by conventional study approaches.
    1. Cancer Biology
    2. Developmental Biology

    Study identifies potential target for treating childhood blood cancer

    Research into a type of blood cancer called juvenile myelomonocytic leukaemia suggests anti-inflammatory treatment as a possible new therapy for the disease.
    1. Biochemistry and Chemical Biology

    Marine sponge chemical and synthetic derivatives hijack human enzyme to kill cells

    New insights on how a human enzyme that converts chemicals produced by marine sponges and optimised synthetic derivatives into cell-killing compounds could aid the development of new anti-cancer or anti-infection drugs.
  1. Media coverage: April roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in April 2022, including BBC News, Sky News and The Sun.
    1. Evolutionary Biology
    2. Genetics and Genomics

    Scientists identify genetic variants linked to mobility changes in aging

    Genetic variants in an enzyme that is important to mitochondrial function may contribute to whether individuals maintain or lose strength and mobility as they age.
  2. eLife welcomes Fiona Hutton as new Head of Publishing

    A long-time advocate for open science, Hutton will lead eLife’s transformation to a ‘publish, then review’ model that puts preprints first.
    1. Cancer Biology

    How air pollution alters lung tissue, increasing cancer susceptibility

    Findings highlight a potential new target for preventing lung disease caused by air pollution.
  3. Media coverage: March roundup of eLife papers in the news

    High-profile news coverage that eLife papers generated in March 2022, including BBC Newsround, Daily Express and Earth.
    1. Genetics and Genomics
    2. Medicine

    How accelerated biological aging may cause bowel cancer

    Study suggests that accelerated aging of an epigenetic clock may increase bowel cancer risk, with implications for developing ways to slow this process.