Multiple non-redundant features of non-rapid eye movement sleep are altered in schizophrenia and largely independent of waking electrophysiological abnormalities, supporting the promise of neuropsychiatric disease biomarkers based on a precise dissection of the sleep.

LncRNAs are important to stabilize postmitotic cell fate of spinal motor neurons.

Genetic analyses illustrate the novel requirement of Ftz-f1 and Sim in adult Drosophila ovaries for regulating follicle cell differentiation and ovulation that is likely conserved in mammals.

AIDPS derived by 76 machine-learning algorithm combinations in 13 independent multicenter cohorts exhibited superior capability than clinical traits and 86 published prognostic signatures and could serve as an ideal biomarker for stratified management and individualized treatment of pancreatic cancer.

In humans, non-crossover gene conversion events transmit GC alleles in 68% of cases and exhibit a complex pattern of multiple disconnected tracts clustered within 20–30 kilobase intervals.

Overexpression of inhibitor of Bruton's tyrosine kinase contributes to the process of tumorigenesis by amplifying translation, represents a promising target for anti-cancer therapies.

Mice with a mutation that disrupts the release of growth hormone show greatly increased lifespan, which can be further increased by caloric restriction.

Radial alignment in confined cell monolayers with isotropic actin network is found to be mediated by the condensation tendency and tissue-scale actin gradient.

A user-friendly pipeline for analysis of time-lapse imaging data from the microfluidic mother machine.

Temperature, the presence of an enemy species and the density of the mutualistic partner species interact to determine the expression of a protective mutualism.