Hybridization probe capture is useful for discovery and surveillance of novel coronaviruses, and its unique strengths complement existing methods like amplicon sequencing and deep metagenomic sequencing.

Tiled-ClickSeq provides a simple and novel next-generation sequencing approach for complete genome sequencing of viruses including SARS-CoV-2, whilst capturing RNA recombination events and minority variants.

Genetic variations that underlie common autoimmune disease genes are predominantly regulatory and modify the expression of multiple genes within the HLA gene complex and throughout the immune system.

Targeted expression of molecular probes for gene expression and chromatin accessibility in subpopulations of neurons in the Drosophila olfactory system identifies genes required for their development and function.

Different subtypes of projection neurons in the mouse olfactory bulb are defined by distinct gene expression patterns and transcription factor networks.

Single-cell transcriptomic analysis reveals novel regenerative endothelial cell populations that mediate remarkably rapid and complete microvascular repair in a novel model of acute lung injury induced by endothelial cell ablation.

BRD9 provides the first actionable therapeutic target in synovial sarcoma tumours that is both biochemically and functionally linked to the SS18-SSX fusion protein which drives disease development.

Combined evidence of human genetics, in vitro cardiomyocyte differentiation, and mouse model indicates that SORBS2 is a regulator of second heart field development and its deficiency causes seemingly opposite atrial septal defects.

The application of real-time genomics by long-read nanopore sequencing to environmental samples creates a new trajectory for non-invasive genomics-based monitoring of critically endangered wildlife.

CUT&RUN (Cleavage Under Targets & Release Using Nuclease) profiles antibody-targeted DNA-binding proteins in situ with high resolution and low background, providing a simple, robust and scalable alternative to chromatin immunoprecipitation.