SerialFIB is an adaptable open-source software designed for streamlining, advanced development and automation of cryo-focused ion beam-based cellular preparations for in situ cryo-electron tomography.
Miriam Romagosa, Sharon Nieukirk ... Mónica A Silva
The rapid and gradual fin whale songs changes adopted by individuals of a certain area provide evidence of vocal learning in this species, elucidate patterns of song evolution and hints on the limits of song variation.
A novel mechanism of gene regulation is discovered wherein a specific long non-coding RNA abolishes the blocking activity of chromatin insulator in the Drosophila HOX gene cluster.
Implementation and characterisation of plasma-focused ion beams for volumetric imaging of cryogenically preserved cells and tissues for ultrastructural examination in their native state.
A biochemical approach unveils the overall shape of a subclass of heavy-metal transporting pumps, thereby shedding light on principle molecular determinants linked to the transport mechanism of these elusive machines, information that is critical well beyond basic science.
Jennifer L Fogel, Daniel L Lakeland ... Francesca V Mariani
Specification and expansion during rib development is explained by Agent-Based Modeling while respecting the locality of decision-making that occurs as millions of cells coordinate their behavior to form and refine spatial pattern.