An under-studied microtubule-associated protein is found to regulate axon growth and branching by modulating microtubule-based organelle transport through its dual interactions with microtubules and the conventional kinesin motor.

The ATPase Fap7 prefabricates a uS11:eS26 ribosomal protein complex for ribosome assembly.

GDNF receptor-expressing mesenchymal progenitor subpopulation within skeletal muscle responds to peripheral nerve injury by sensing GDNF and secreting BDNF, thereby directly promoting nerve regeneration through facilitating remyelination by Schwann cells.

Daily palovarotene treatment reduces pathogenic expansion of fibro/adipogenic progenitors but results in long bone growth plate loss and overgrowths of synovial cartilage in juvenile mice.

Fibro-adipogenic progenitors in skeletal muscle contribute to the neuromuscular pathogenesis of spinal muscular atrophy, and depletion of SMN in chondrocytes reduces local IGF sigaling in growth plate.

The function and distribution of kinesin motors on exocytotic vesicles is dissected and visualized through a combination of gene knockout experiments, high-resolution microscopy and advanced data analysis.

Genetic effects on body weight in mice are highly heterogeneous, dynamic, and nonlinear with respect to genomic background, age, and diet.

A vasoactive molecular imaging probe provides capability for sensitive functional imaging of cancer-associated protease activity in vivo.

Blocking an atrophic 'master regulator' pathway following tendon tear does not affect resulting skeletal muscle atrophy.

CRISPR/Cas9 gene-editing was used to generate a novel endogenous pH-sensitive EGF receptor chimera with the unique utility to study receptor endocytosis in a single-cell and high-throughput experimental formats.