Altering the level of different oncogenic mutants of Kras induces unique tumor patterns in mice, suggesting that tissue-specific responses mold the sensitivity of normal tissues to different oncogenic RAS mutations.

A novel process by which counter-regulatory glucagon release is regulated in both mouse and human.

A G1 cyclin shows key properties expected of a protein that could link cell cycle progression to cell growth.

Uncovering a mechanism for how inflammatory signaling is opposed by a phosphatase identifies a potential druggable target to treat E. coli sepsis.

A viral protein hijacks the key effector of transcriptional gene silencing, Su(var)3-9, to evade host plant surveillance.

A tissue-wide fluoresence-based screen reveals that not all tissues in an organism (Drosophila) reinforce a hierarchy of codon usage to the same extent, a finding which impacts tissue-specific protein expression and function.

A computational model, based on single-cell features like contractility and polarizability, quantitatively describes cellular dynamics from the single cell level up to small cohorts and confluent tissues.

Opposing gradients of activin A and follistatin within the spiral shaped mammalian cochlea instruct the graded pattern of mechano-sensory hair cell formation.

RNA chaperone Hfq dynamically binds various pools of cellular RNAs to execute different regulatory functions.

Endothelial dysfunction due to cardiovascular disease risk factors explained by cardiac endothelial cell transcriptome remodelling.