1,197 results found
    1. Developmental Biology
    2. Plant Biology

    Three ancient hormonal cues co-ordinate shoot branching in a moss

    Yoan Coudert, Wojtek Palubicki ... C Jill Harrison
    The mosses and angiosperms have independently evolved mechanisms that use the same hormones-auxin, cytokinin and strigolactone-to regulate lateral shoot branching.
    1. Developmental Biology

    Branching morphogenesis in the developing kidney is not impacted by nephron formation or integration

    Kieran M Short, Alexander N Combes ... Ian M Smyth
    Analysing developing mouse kidneys demonstrates nephron formation does not significantly impact branching morphogenesis of the ureteric bud, suggesting this process is distinct from branching in organs like the mammary gland.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Biochemical reconstitution of branching microtubule nucleation

    Raymundo Alfaro-Aco, Akanksha Thawani, Sabine Petry
    The protein TPX2 and the protein complex augmin together recruit the microtubule nucleator γ-TuRC to a pre-existing microtubule where they initiate branching microtubule nucleation.
    1. Developmental Biology

    VEGF/VEGFR2 signaling regulates hippocampal axon branching during development

    Robert Luck, Severino Urban ... Carmen Ruiz de Almodóvar
    Hippocampal axon branching, required for the formation of functional neuronal networks, is regulated by VEGF/VEGFR2 signaling during development.
    1. Developmental Biology

    YAP is essential for mechanical force production and epithelial cell proliferation during lung branching morphogenesis

    Chuwen Lin, Erica Yao ... Pao-Tien Chuang
    The control of local cell properties such as epithelial cell number and mechanical force production by Hippo signaling is a major determinant of lung branching.
    1. Neuroscience

    Regulation of branching dynamics by axon-intrinsic asymmetries in Tyrosine Kinase Receptor signaling

    Marlen Zschätzsch, Carlos Oliva ... Bassem A Hassan
    Asymmetric localization of the receptor EGFR within branches of axons is required to establish the precise wiring of neuronal networks within the Drosophila brain.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    The intrinsically disordered cytoplasmic tail of a dendrite branching receptor uses two distinct mechanisms to regulate the actin cytoskeleton

    Daniel A Kramer, Heidy Y Narvaez-Ortiz ... Baoyu Chen
    The dendrite branching receptor HPO-30 modulates actin dynamics by binding to both WAVE complex and actin filaments.
    1. Neuroscience

    Deletion of a kinesin I motor unmasks a mechanism of homeostatic branching control by neurotrophin-3

    Thomas O Auer, Tong Xiao ... Filippo Del Bene
    Disrupting synapse formation between the retina and the brain in zebrafish larvae-by eliminating the molecular motor Kif5A-triggers a compensatory increase in the branching of retinal axons aimed at restoring synapse number.
    1. Cell Biology
    2. Developmental Biology

    Coordinated crosstalk between microtubules and actin by a spectraplakin regulates lumen formation and branching

    Delia Ricolo, Sofia J Araujo
    Lumen formation by single epithelial cells depends on FGF-signalling-dependent expression of a spectraplakin, which can be functionally replaced by Tau.
    1. Computational and Systems Biology
    2. Developmental Biology

    Synchronization of endothelial Dll4-Notch dynamics switch blood vessels from branching to expansion

    Benedetta Ubezio, Raquel Agudo Blanco ... Holger Gerhardt
    Increasing levels of the growth factor Vegfa disrupt blood vessel branching morphogenesis and drive diameter increase by synchronizing Notch signalling fluctuations between endothelial cells.

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