Noriko Ichino, MaKayla R Serres ... Stephen C Ekker
The analysis of the first 1000 revertible protein trap alleles in zebrafish resulted in new functional genomic annotations and produced a panel of potential new models of human disease.
Liang-Yu Pang, Steven DeLuca ... Allan C Spradling
Chromatin changes downstream from Drosophila germline stem cells and fertilized zygotes alter how transposable element activity and gene expression are controlled to facilitate differentiation.
Transposition reactions that occur during DNA replication and involve the termini of adjacent transposons can induce genome expansion by re-replication of transposon-flanking sequences.
Fusion proteins composed of the Sleeping Beauty transposase and catalytically inactive Cas9 target transposon integration into genomic regions specified by single guide RNAs.
The genome sequence of Trichoplusia ni enables the use of this widespread lepidopteran pest as a model for both the study of small RNA pathways and insecticide resistance.
Dnajb6 is identified as a novel sick sinus syndrome causative gene that exhibits a unique expression pattern within a subpopulation of sinus node pacemaker cells.