122 results found
    1. Developmental Biology

    Building the vertebrate codex using the gene breaking protein trap library

    Noriko Ichino, MaKayla R Serres ... Stephen C Ekker
    The analysis of the first 1000 revertible protein trap alleles in zebrafish resulted in new functional genomic annotations and produced a panel of potential new models of human disease.
    1. Developmental Biology

    Chromatin and gene expression changes during female Drosophila germline stem cell development illuminate the biology of highly potent stem cells

    Liang-Yu Pang, Steven DeLuca ... Allan C Spradling
    Chromatin changes downstream from Drosophila germline stem cells and fertilized zygotes alter how transposable element activity and gene expression are controlled to facilitate differentiation.
    1. Chromosomes and Gene Expression
    2. Plant Biology

    Transposition-mediated DNA re-replication in maize

    Jianbo Zhang, Tao Zuo ... Thomas Peterson
    Transposition reactions that occur during DNA replication and involve the termini of adjacent transposons can induce genome expansion by re-replication of transposon-flanking sequences.
    1. Biochemistry and Chemical Biology

    RNA-guided retargeting of Sleeping Beauty transposition in human cells

    Adrian Kovač, Csaba Miskey ... Zoltán Ivics
    Fusion proteins composed of the Sleeping Beauty transposase and catalytically inactive Cas9 target transposon integration into genomic regions specified by single guide RNAs.
    1. Physics of Living Systems

    IS200/IS605 Family-Associated TnpB Increases Transposon Activity and Retention

    Davneet Kaur, Thomas E. Kuhlman
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology

    Yu Fu, Yujing Yang ... Phillip D Zamore
    The genome sequence of Trichoplusia ni enables the use of this widespread lepidopteran pest as a model for both the study of small RNA pathways and insecticide resistance.
    1. Genetics and Genomics

    A phenotype-based forward genetic screen identifies Dnajb6 as a sick sinus syndrome gene

    Yonghe Ding, Di Lang ... Xiaolei Xu
    Dnajb6 is identified as a novel sick sinus syndrome causative gene that exhibits a unique expression pattern within a subpopulation of sinus node pacemaker cells.
    1. Developmental Biology
    2. Genetics and Genomics

    Drosophila p53 isoforms have overlapping and distinct functions in germline genome integrity and oocyte quality control

    Ananya Chakravarti, Heshani N Thirimanne ... Brian R Calvi
    Drosophila p53 protein isoforms function during oogenesis to ensure the integrity of the transmitted genome, a function that is conserved to humans.

Refine your results by:

Type
Research categories