Direct-to-consumer genetic genealogy services that allow users to upload their own datasets are vulnerable to attacks on genetic privacy that exploit the structure of genetic variation.

Two studies suggest that a determined adversary may be able to obtain genetic information that they should not have permission to access from some genealogy databases.

Shh, produced by postmitotic spinal neurons, plays crucial roles in the specification of the lateral motor column of the spinal cord through ARHGAP36.

A computer model built on insights gained from comprehensive experimental analysis reveals mechanisms of blood stem cell regulation.

A previously unknown oncogenic feature of an embryonic transcription factor was uncovered from transcriptomic analysis of tumors that lack functional Polycomb silencing.

Stage identity and developmental progression in insects is controlled by sequential expression of temporal-specific transcription factors.

A nuclear Non-stop identity complex (NIC) supervises enterocyte (EC) identity, preserves tissue homeostasis, and prevents premature aging by maintaining EC-specific gene expression, silencing non-relevant programs, and safeguarding large-scale nuclear organization.

Peripheral injury induces a programmed but reversible transformation of gene expression in somatosensory neurons providing a mechanism to regulate sensory input during wound healing.

Genetic and epigenetic editing experiments establish causal links between transposon-derived enhancers and gene regulation in mouse embryonic and extraembryonic lineages.

The Drosophila equivalent of the human protein Mixed Lineage Leukemia 1n enables neural stem cells to generate neural progenitors through the fly equivalent of the human transcription factor Sp8, thereby contributing to an increased number and diversity of cell types during brain development.