Acetylation of the circadian transcription factor BMAL1 by the acetyltransferase TIP60 is crucial for recruitment of the pause release factors to clock gene promoters and productive elongation of these genes.

Salicylic acid, the precursor to aspirin, is an anti-tumor agent that blocks protein acetylation.

The lysine acetyltransferases KAT2A and KAT2B regulate the dynamic chromatin association of the tumour suppressor protein PALB2, protecting active genes and promoting DNA damage repair in a context-dependent manner.

Acetylation stabilizes a fungal effector to mis-localize a key defense protein, leading to compromised immunity of host plants.

The interrogation of histone modifications on DNA barcodes enables efficient and direct screening for epigenetic regulators in thousands of mutants in parallel.

Mass spectroscopy, molecular modeling and/or molecular dynamics simulations reveal how acetylation regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation.

Global proteomic and acetylomic analyses reveal how skeletal muscle adapts to high-intensity interval training including adaptations to processes regulating metabolism and contraction.

AhCobQ, a novel bacterial lysine deacetylase, functions independently of NAD+ and Zn2+, revealing a previously unknown domain and broad implications for metabolic regulation in prokaryotic systems.

We applied a combined synthetic biological, biochemical and mass-spectrometric approach to show that YcgC is not a member of a novel lysine deacetylase class in prokaryotes.

Alternative splicing of a single gene generates functional diversity amongst chromatin regulators.