A PEP risk scoring model that could be calculated before ERCP, SuPER model, may aid in preventing PEP by allowing selection of the appropriate expert endoscopist and useful PEP prophylaxes.

Proteomic profiling of extracellular vesicle proteins from patients with benign and malignant pancreatic diseases offers a valuable resource for identifying biomarkers for pancreatic cancer detection.

Smoking is a risk factor for a broad range of gastrointestinal diseases independent of alcohol consumption.

By regulating acinar cell differentiation, the transcription factor PTF1A acts as a novel class of tumor suppressor in pancreatic cancer.

Single-cell RNA-sequencing analyses and functional studies define heterogeneity within the pancreatic ductal tree and unique properties of subpopulations of duct cells including an epithelial-mesenchymal transcriptomic axis and roles in chronic pancreatic inflammation.

Arid1a loss in the pancreas enables an irreversible reprogramming of cell fate that is dependent on both cellular and genetic context.

In the pancreas, reciprocal interactions between epithelial cells and myeloid cells determine the balance between tissue repair and carcinogenesis by regulating acinar cell plasticity through differential activation of EGFR/MAPK signaling.

Genetic lineage tracing approach combined with live imaging visualized the functional stem cell activity of Doublecortin-like kinase 1⁺ cells within pancreatic cancer in vivo.

Cells from the human pancreatic duct can be grown in culture and triggered to become insulin-producing cells, which could potentially be transplanted into patients with diabetes.