The first non-invasive technique to assess the action of brain clearance mechanisms, driven by the perivascular inflow of cerebrospinal fluid, has been developed using magnetic resonance imaging.

Perivascular extracellular vesicles induce bone repair, and do so via tetraspanin binding to recipient skeletal progenitor cells.

A new brain perivascular cell type in the zebrafish related to mammalian Fluorescent Granular Perithelial (FGP) cells emerges directly from endothelium during early development.

EphrinB2 promotes glioblastoma stem-like cell malignancy through the interplay of cell-autonomous and non-cell-autonomous mechanisms and its targeting suppresses tumourigenesis in preclinical models of human glioblastoma.

Distinctive microenvironments within demyelinated white matter determine fate decisions of adult oligodendrocyte progenitor cells.

Analysis of a mouse model of megalencephalic leukoencephalopathy with subcortical cysts (MLC) shows that the astrocyte-specific membrane protein MLC1 sustains the postnatal development of perivascular astrocytic processes and that MLC is a developmental disorder of the gliovascular unit.

A new tracer infusion method is used to confirm that pulsatile cerebrospinal fluid transport into the brain occurs naturally and is driven by the cardiac cycle, not by tracer injection.

CD107a expression divides osteogenic from adipogenic perivascular precursor cells within human white adipose tissue.

Solute movement in brain extracellular space is determined by solute diffusion, and does not depend on convection or aquaporin-4 expression as predicted by the glymphatic mechanism.

A new type of skin perivascular macrophages with extramedullary origin, access to blood and exclusive anti-inflammatory reparative properties has been characterized.