6,382 results found
    1. Ecology
    2. Evolutionary Biology

    Multiple preferred escape trajectories are explained by a geometric model incorporating prey’s turn and predator attack endpoint

    Yuuki Kawabata, Hideyuki Akada ... Paolo Domenici
    The mathematical model incorporating new parameters explains multimodal distributions in escape direction (i.e., multiple preferred escape trajectories), which are previously observed in various animal taxa.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structure of a bacterial RNA polymerase holoenzyme open promoter complex

    Brian Bae, Andrey Feklistov ... Seth A Darst
    The crystal structure of bacterial RNA polymerase bound to the transcription bubble reveals key features that support the formation of a double-strand/single-strand DNA junction at the upstream edge of the −10 element where bubble formation initiates.
    1. Neuroscience

    Spinal premotor interneurons controlling antagonistic muscles are spatially intermingled

    Remi Ronzano, Sophie Skarlatou ... Marco Beato
    Multiple trans-synaptic tracing methods reveal that there is no spatial segregation between flexor and extensor premotor interneurons in the lumbar spinal cord.
    1. Ecology

    Both prey and predator features predict the individual predation risk and survival of schooling prey

    Jolle Wolter Jolles, Matthew MG Sosna ... Iain D Couzin
    Detailed tracking of live predators attacking live schools of prey reveals the crucial interplay between predator attack strategy and prey behaviour and positioning in determining the predation risk within mobile animal groups.
    1. Cancer Biology
    2. Cell Biology

    Different promoter affinities account for specificity in MYC-dependent gene regulation

    Francesca Lorenzin, Uwe Benary ... Elmar Wolf
    Differences in promoter affinity and MYC levels explain distinct expression profiles induced by physiological and oncogenic MYC.
    1. Ecology

    Fine-scale tracking reveals visual field use for predator detection and escape in collective foraging of pigeon flocks

    Mathilde Delacoux, Fumihiro Kano
    Foveal vision in pigeons plays a crucial role in predator detection while the flock is collectively foraging and being vigilant.
    1. Computational and Systems Biology
    2. Physics of Living Systems

    Intraspecific predator interference promotes biodiversity in ecosystems

    Ju Kang, Shijie Zhang ... Xin Wang
    Intraspecific predator interference enables a wide range of consumer species to coexist with a limited variety of resources, explaining the paradox of the plankton and species diversity patterns across ecosystems.
    1. Chromosomes and Gene Expression
    2. Computational and Systems Biology

    Promoter sequence and architecture determine expression variability and confer robustness to genetic variants

    Hjörleifur Einarsson, Marco Salvatore ... Robin Andersson
    A flexible transcription initiation architecture and a uniform regulatory grammar buffer expression variability and the effects of genetic variants on essential genes while a rigid transcription initiation architecture and a diverse regulatory grammar ensure condition-specific responsiveness of other genes.
    1. Chromosomes and Gene Expression

    The nucleosomal barrier to promoter escape by RNA polymerase II is overcome by the chromatin remodeler Chd1

    Peter J Skene, Aaron E Hernandez ... Steven Henikoff
    The ATP-dependent chromatin remodeler Chd1 controls nucleosome turnover to allow RNA Polymerase to transcribe in vivo.
    1. Chromosomes and Gene Expression

    The chromatin remodelers RSC and ISW1 display functional and chromatin-based promoter antagonism

    Timothy J Parnell, Alisha Schlichter ... Bradley R Cairns
    A combination of genetics, expression, genomic localization, and genomic nucleosome profiling demonstrates antagonism between two chromatin remodelers that reveal different mechanisms at different promoter architectures.

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