Systematic analysis of C. elegans zygotes manipulated to divide equally demonstrates that daughter cell size asymmetry is critical for proper cell cycle timing, positioning, and fates during subsequent embryogenesis.
Anne L Willems, Lukas Van Oudenhove, Bram Vervliet
The unexpected absence of danger is experienced as a pleasurable relief and activates reward-related brain regions in humans, highlighting an overlap in the processing of absent danger and rewards.
A novel methodical approach aimed at improving translation of network analyses to psychopathology provides an intuitive representation of longitudinal clinical pathways between symptoms and can assist in predicting prognosis.
Gary S McDowell, John D Knutsen ... Rebeccah S Lijek
Early career researchers commonly peer review manuscripts on behalf of invited reviewers, often without receiving feedback or being named to the journal.
Participants' subjective beliefs about the treatment received in an intervention study can explain variability in mental health symptoms and cognition.
Simon Desch, Petra Schweinhardt ... Susanne Becker
Endogenous modulation of pain relief perception is based on its motivational content and enhanced by increased dopamine availability with no significant effects of a pharmacological opioidergic manipulation in healthy volunteers.
A systemic hormone controls progenitor fate decisions independent of local fate determining pathways in the adult intestinal stem cell niche of Drosophila melanogaster..
The linguistic characteristics of peer review reports are not influenced by research area, type of review or reviewer gender, which is evidence for the robustness of peer review.