Browse our latest Cell Biology articles

Page 118 of 333
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Vaccine-induced COVID-19 mimicry syndrome

    Eric Kowarz, Lea Krutzke ... Rolf Marschalek
    The Spike gene expressed by the vector-based vaccine Vaxzevria bears the risk of cryptic splicing, which in turn may lead to cellular production of soluble, instead of membrane-anchored, Spike protein variants.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Eco1-dependent cohesin acetylation anchors chromatin loops and cohesion to define functional meiotic chromosome domains

    Rachael E Barton, Lucia F Massari ... Adèle L Marston
    Meiotic recombination and chromosome segregation require the establishment of chromatin boundaries by the acetyltransferase Eco1, which anchors both chromatin loops and cohesion.
    1. Cell Biology
    2. Immunology and Inflammation

    Functional visualization of NK cell-mediated killing of metastatic single tumor cells

    Hiroshi Ichise, Shoko Tsukamoto ... Michiyuki Matsuda
    Live imaging of the duel of an NK cell versus a metastatic cancer cell on pulmonary epithelial cells reveals a novel survival tactics adopted by cancer cells.
    1. Cell Biology
    2. Medicine

    Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes

    Xiaowei Zheng, Sampath Narayanan ... Sergiu-Bogdan Catrina
    The repression of HIF-1 plays a central role in mitochondrial reactive oxygen species (ROS) overproduction and subsequent tissue damage in diabetes, which is mediated by increased mitochondrial respiration, making HIF-1 signaling an attractive therapeutic target for diabetes complications.
    1. Cancer Biology
    2. Cell Biology

    Intravital deep-tumor single-beam 3-photon, 4-photon, and harmonic microscopy

    Gert-Jan Bakker, Sarah Weischer ... Peter Friedl
    Infrared high-pulse-energy low-pulse-repetition-rate excitation advances deep intravital microscopy in strongly scattering tissues such as skin tumors and thick bone, thereby bringing previously inaccessible tumor areas in reach with subcellular resolution.
    1. Cell Biology

    Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14, and Sic1 for origin licensing in S. cerevisiae

    Jasmin Philip, Mihkel Örd ... Amy E Ikui
    Pre-RC component Cdc6 is primed for origin licensing by phosphatases and Cdk1 inhibitor.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Structural basis for cytoplasmic dynein-1 regulation by Lis1

    John P Gillies, Janice M Reimer ... Samara L Reck-Peterson
    A 3.1 Å structure of cytoplasmic dynein-1 in complex with its regulator Lis1 reveals the interfaces between dynein and Lis1, all of which are important for dynein function in vitro and in vivo.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Adaptation of the periplasm to maintain spatial constraints essential for cell envelope processes and cell viability

    Eric Mandela, Christopher J Stubenrauch ... Iain D Hay
    The bacterial periplasm must adapt to factors effecting the width of the cell envelope.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae

    Aftab Nadeem, Alexandra Berg ... Sun Nyunt Wai
    MakA, a pore-forming cytotoxin produced by Vibrio cholerae, forms oligomers and remodels membranes into high-curvature tubes, resulting in membrane integrity loss inside acidified organelle lumens or when cultured with cells in an acidic medium.
    1. Cell Biology
    2. Genetics and Genomics

    Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis

    Catalina Pereira, Gerardo A Arroyo-Martinez ... Robert S Weiss
    Alternative 9-1-1 complexes have evolved to play essential roles in mammalian meiosis and function to activate the protein kinase ATR and promote key meiotic events necessary for fertility.