Browse our latest Cell Biology articles

Page 127 of 320
    1. Cell Biology

    A signal capture and proofreading mechanism for the KDEL-receptor explains selectivity and dynamic range in ER retrieval

    Andreas Gerondopoulos, Philipp Bräuer ... Simon Newstead
    KDEL receptor structures with variant HDEL and RDEL signals help decode the cell biological mechanism for the selective retrieval of escaped endoplasmic reticulum luminal proteins.
    1. Cancer Biology
    2. Cell Biology

    A novel mitochondrial Kv1.3–caveolin axis controls cell survival and apoptosis

    Jesusa Capera, Mireia Pérez-Verdaguer ... Antonio Felipe
    The association of caveolin with the potassium channel Kv1.3 fine-tunes cell survival and apoptosis.
    1. Cell Biology
    2. Neuroscience

    The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia

    Katalin Skrapits, Miklós Sárvári ... Erik Hrabovszky
    Neuroanatomical studies reveal presence and cholinergic phenotype of 150,000-200,000 extrahypothalamic gonadotropin-releasing hormone neurons in human basal ganglia and basal forebrain, and RNA-sequencing detects gonadotropin-releasing hormone receptor-1 expression in cholinergic interneurons but not in spiny projection neurons of the human putamen.
    1. Cell Biology
    2. Developmental Biology

    Apical PAR complex proteins protect against programmed epithelial assaults to create a continuous and functional intestinal lumen

    Maria Danielle Sallee, Melissa A Pickett, Jessica L Feldman
    During intestinal development, apical PAR complex proteins keep apical domains and junctions continuous between cells as they divide and elongate, and ultimately build a continuous functional tube.
    1. Cell Biology
    2. Medicine

    The Ca2+-activated cation channel TRPM4 is a positive regulator of pressure overload-induced cardiac hypertrophy

    Yang Guo, Ze-Yan Yu ... Boris Martinac
    The TRPM4 ion channel has been identified as an important component in the causation of mechanical pressure overload-induced pathological left ventricular hypertrophy, which is a powerful predictor of cardiovascular mortality.
    1. Cell Biology
    2. Medicine

    Pigmentation: Watching hair turn grey

    Michael P Philpott
    Analysing changes in hair pigmentation may lead to a better understanding of the impacts of ‘life events’ on human biology and aging.
    Version of Record
    Insight
    1. Cancer Biology
    2. Cell Biology

    Science Forum: Nanoscape, a data-driven 3D real-time interactive virtual cell environment

    Shereen R Kadir, Andrew Lilja ... John McGhee
    Computer visualization techniques developed for video games can be repurposed to enable viewers to explore cells and their environment in three dimensions.
    1. Cell Biology
    2. Developmental Biology

    Protein-based condensation mechanisms drive the assembly of RNA-rich P granules

    Helen Schmidt, Andrea Putnam ... Geraldine Seydoux
    P granule assembly depends in part on protein-protein interactions that drive condensation independent of RNA.
    1. Cell Biology

    Scaling of subcellular actin structures with cell length through decelerated growth

    Shane G McInally, Jane Kondev, Bruce L Goode
    The size of a subcellular structure, yeast actin cables, scales with the linear dimensions of the cell, which is achieved by feedback control of their growth rate.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

    Amy R Strom, Ronald J Biggs ... Andrew D Stephens
    Micromanipulation experiments demonstrate that HP1α strengthens interphase and mitotic chromosome mechanics and maintains nuclear shape by chromatin crosslinking, separate from histone methylation.