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T-cell receptor signaling actively regulates gating of the nuclear pore complex (NPC) in T cells by inducing translocation of protein kinase C-θ to the NPC to promote the sumoylation of RanGAP1.

Structural rearrangements of meiotic spindles during the transition from metaphase to anaphase can be controlled by local changes of microtubule dynamics, such as nucleation and/or turnover, and that katanin promotes microtubule turnover by severing microtubules near the chromosomes.

The density of the cytoplasm in S. pombe varies in time and space during the cell cycle through modulation of tip growth rate coupled with constant mass growth rate.

A method to profile hair pigmentation patterns establishes a new approach for psychobiological studies and links metabolic changes to greying in humans.

SIRT1, a cellular metabolic sensor, transcriptionally promotes sphingomyelin degradation in embryonic stem cells, which in turn modulates their membrane fluidity and neural differentiation.

The transcription factor Snai1b maintains the myocardial wall integrity by limiting cell extrusions and regulating the intermediate filament gene desmin b.

The transcriptional landscape of epicardial cells revealed 11 cell populations that differentially expressed early cardiac genes and numerous cardioprotective paracrine factors defining their regenerative potential.

A high-fidelity and efficient strategy to use CRISPR/Cas9 to reversibly insert large DNA fragments into somatic cells to label or modify endogenous proteins for research and, in the future, for gene therapy.

A GPCR activated by the same agonist engages different conformational biosensors at different subcellular locations, suggesting that location-based conformations drive spatial encoding of signaling.

Upregulation of circPTPN12 in endometrial epithelial cells (EECs) of fibrotic endometrium sponged miR-21–5 p and resulted in upregulation of its target gene, ΔNp63α, which induced transition of EECs to mesenchymal cells.