Eugene A Katrukha, Daphne Jurriens ... Lukas C Kapitein
Quantitative super-resolution light microscopy reveals the relative abundance and three-dimensional organization of different microtubule subsets within dendrites of mammalian neurons.
The LIN37-DREAM complex has a critical role in regulating DNA double-strand break end processing and suppressing aberrant homology-directed repair in quiescent cells.
Mor Levi-Ferber, Rewayd Shalash ... Sivan Henis-Korenblit
Neuronal circuits can be disrupted by ire-1-dependent mRNA decay to affect germline tumor cell identity by regulating cross-tissue communication in Caenorhabditis elegans.
A smooth and circular interface can form between domains of the cell cortex from local induction of a contractile actomyosin ring by centrifugal pushing forces of an expanding Arp2/3 actin network.
Eléanor Simon, Carlos Jiménez-Jiménez ... Isabel Guerrero
The glypicans Dally-like protein and Dally reveal functional non-redundancy of the Hedgehog co-receptors Boi and Ihog through independent interactions and specifically regulate cytoneme dynamics via the Ihog FNIII domain, thus setting long-range signaling.
Loss of the F-ATP synthase c-subunit inhibits a pathological mitochondrial permeability transition pore that is coupled to a maladaptive mitochondrial unfolded protein response while also extending lifespan.