Browse our latest Cell Biology articles

Page 133 of 320
    1. Cell Biology

    UBTD1 regulates ceramide balance and endolysosomal positioning to coordinate EGFR signaling

    Stéphanie Torrino, Victor Tiroille ... Stephan Clavel
    UBTD1 coordinates EGFR signaling by modulating ceramides level through ASAH1 ubiquitination and EGFR degradation through SQSTM1/p62 ubiquitination, which together impact cell proliferation.
    1. Cell Biology
    2. Physics of Living Systems

    How cells determine the number of polarity sites

    Jian-geng Chiou, Kyle D Moran, Daniel J Lew
    Minimal essential features of Rho GTPase systems are elucidated that regulate the number of distinct domains developed by a cell’s polarity machinery, which in turn governs cell shape.
    1. Cell Biology
    2. Immunology and Inflammation

    Molecular tracking devices quantify antigen distribution and archiving in the murine lymph node

    Shannon M Walsh, Ryan M Sheridan ... Beth Ann Jiron Tamburini
    Antigen-phosphorothioate DNA conjugation provides a vaccination strategy where stable barcodes facilitate the detection and quantification of antigen using single-cell RNA sequencing.
    1. Cell Biology

    Compartment-specific opioid receptor signaling is selectively modulated by different dynorphin peptides

    Jennifer M Kunselman, Achla Gupta ... Manojkumar A Puthenveedu
    Different dynorphins, which signal similarly from the cell surface, can differentially localize G protein-coupled receptors to specific subcellular compartments and cause divergent receptor fates and distinct spatiotemporal patterns of signaling.
    1. Cell Biology
    2. Developmental Biology

    EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice

    Yuki Osawa, Kazuya Murata ... Fumihiro Sugiyama
    EXOC1 contributes to the proper differentiation balance of spermatogonial stem cells and spermatocyte syncytia formation by regulating the morphology of male germ cells.
    1. Cell Biology
    2. Neuroscience

    The role of sigma 1 receptor in organization of endoplasmic reticulum signaling microdomains

    Vladimir Zhemkov, Jonathon A Ditlev ... Ilya Bezprozvanny
    Signaling function of sigma 1 receptor is related to its ability to organize cholesterol-enriched microdomains in the endoplasmic reticulum membrane.
    1. Cell Biology

    A robust method for particulate detection of a genetic tag for 3D electron microscopy

    James Rae, Charles Ferguson ... Robert G Parton
    Development of a new system for gold particle detection of a genetic tag for electron microscopy.
    1. Cell Biology

    SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation

    David W Sanders, Chanelle C Jumper ... Clifford P Brangwynne
    A high-throughput microscopy screen for drugs that modulate SARS-CoV-2 spike-mediated membrane fusion identifies an essential role for cholesterol in both virus entry and syncytia formation.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Coordination between nucleotide excision repair and specialized polymerase DnaE2 action enables DNA damage survival in non-replicating bacteria

    Asha Mary Joseph, Saheli Daw ... Anjana Badrinarayanan
    Live-cell imaging shows that replication-independent specialized polymerase action is a consequence of lesion processing via NER and impacts cellular survival under stress outside replicative phases of the cell cycle.
    1. Cell Biology
    2. Structural Biology and Molecular Biophysics

    Membrane binding controls ordered self-assembly of animal septins

    Agata Szuba, Fouzia Bano ... Gijsje H Koenderink
    Nanoscaleimaging reveals that animal septins form dense filamentous networks on biomimeticlipid membranes, explaining how septins may regulate cell surface rigidity.