Saima Usman, William Andrew Yeudall ... Ahmad Waseem
Disruption of vimentin–actin interaction induces XIST expression and drives epithelial-to-mesenchymal transition and stem cell-like traits in breast cancer cells, enhancing oncogenic behaviour in nude mice independent of oestrogen.
Leonid Peshkin, Enrico maria Daldello ... Catherine Jessus
A comprehensive resource describes protein abundance and phosphorylation dynamics during Xenopus oocyte maturation, serving as an essential tool for investigating the molecular mechanisms driving meiotic progression.
Changes in the pericyte pool after stroke affect the restoration of the blood-brain barrier function and brain self-repair, and offer a new approach to therapy.
Sakura is expressed in female germlines, interacts with Otu, and is crucial for germline stem cell renewal and differentiation and oogenesis in Drosophila.
Dylan A Valencia, Angela N Koeberlein ... Margot E Quinlan
Complementary biochemical and cell-biological approaches reveal that formin FHOD3-mediated actin elongation, rather than nucleation, is critical for maintaining cardiomyocyte sarcomeres.
Polyunsaturated fatty acids are not genetically replaceable in the nematode C. elegans and only mutations that help free ferrous ions can boost the activity of a poorly functioning desaturase enzyme.
