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Subcellular sequestration of caspase near membrane-associated proteins enables its non-lethal activation, which modulates neuronal function and innate olfactory behavior in the adult Drosophila olfactory receptor neurons.

Upregulated by HOXA10, RUNX2 isoform II transactivates PRDX2 expression and inhibits ferroptosis and apoptosis in oral squamous cell carcinoma.

Phosphorylation of the kinesin-2 motor protein’s elbow region by NEKL-3 kinase maintains autoinhibition, enabling its transport to cilia for sensory function.

Genome-wide epigenetic profiling reveals chromatin regions in the human myometrium involved in functional regulation and hormonal control during pregnancy.

ER aggregates confined in the nucleus are cleared via ER reorganization when cells progress through mitosis and cytokinesis.

Functional analyses reveal the HNF4α-TET2-FBP1 axis as a critical regulator of gluconeogenesis, type 2 diabetes (T2D) progression, and metformin’s therapeutic effects, which proposes TET2 as a promising therapeutic target for T2D.

The development of an automated micronucleus segmentation program enables population-level comparisons between cells with and without micronuclei and defines a highly limited response to micronucleus formation or rupture.

Nervous necrosis virus typically enters host cells via endocytosis, but it can also enter via a process called macropinocytosis.