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Page 19 of 328
    1. Cell Biology
    2. Neuroscience

    Cell-to-cell signalling mediated via CO2: activity dependent CO2 production in the axonal node opens Cx32 in the Schwann cell paranode

    Jack Butler, Lowell Mott ... Nicholas Dale
    Not revised
    Reviewed Preprint v1
    • Important
    • Solid
    1. Cell Biology

    N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation

    Alaknanda Emery, Orest W Blaschuk ... Darryl L Russell
    A critical role for N-cadherin in ovarian follicular development and ovulation is demonstrated with inhibitors or knockout of N-cadherin shown to inhibit ovulation by blocking mechanotransduction of ovulatory genes.
    1. Cell Biology
    2. Neuroscience

    Development of the axonal βII-spectrin periodic skeleton requires active cytoskeletal remodelling

    Shivani Bodas, Ashish Mishra ... Aurnab Ghose
    Not revised
    Reviewed Preprint v1
    • Useful
    • Convincing
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    A biochemical mechanism for Stu2/XMAP215-family microtubule polymerases

    Binnu Gangadharan, Daniel L Kober, Luke M Rice
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cancer Biology
    2. Cell Biology

    Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer

    Chong Zhang, Zuoyan Zhang ... Yangling Li
    Uncovering a novel PDE1A/YTHDF2/STAT3 pathway in non-small cell lung cancer (NSCLC) progression also provides therapeutic strategies for treating NSCLC patients with metastasis.
    1. Cell Biology

    Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation

    Yuma Cho, Akari Taniguchi ... Junichi Ikenouchi
    The Rho-ROCK–matriptase signaling axis promotes claudin release from EpCAM/TROP2 complexes, enabling tight junction reassembly during epithelial remodeling to preserve barrier integrity.
    1. Cell Biology

    Targeting the WSB2–NOXA axis in cancer cells for enhanced sensitivity to BCL-2 family protein inhibitors

    Dongyue Jiao, Kun Chang ... Chenji Wang
    Disrupting WSB2-mediated NOXA degradation sensitizes cancer cells to apoptosis and provides a new strategy to overcome resistance to BCL-2 inhibition.
    1. Cell Biology
    2. Physiology

    Lymphatic System: Closing in on pacemaker cells

    Pin-Ji Lei, Timothy P Padera
    Lymphatic muscle cells orchestrate the contraction of collecting lymphatic vessels in mice.
    Version of Record
    Insight
    1. Cancer Biology
    2. Cell Biology

    A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial–mesenchymal transition and stemness in breast cancer

    Saima Usman, William Andrew Yeudall ... Ahmad Waseem
    Disruption of vimentin–actin interaction induces XIST expression and drives epithelial-to-mesenchymal transition and stem cell-like traits in breast cancer cells, enhancing oncogenic behaviour in nude mice independent of oestrogen.
    1. Cell Biology
    2. Immunology and Inflammation

    G1 and G2 ApolipoproteinL1 modulate macrophage inflammation and lipid accumulation through the polyamine pathway

    Esther Liu, Matthew Wright ... Jennie Lin
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
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