Browse our latest Cell Biology articles

Page 223 of 327
    1. Cell Biology
    2. Plant Biology

    Stromule extension along microtubules coordinated with actin-mediated anchoring guides perinuclear chloroplast movement during innate immunity

    Amutha Sampath Kumar, Eunsook Park ... Jeffrey Lewis Caplan
    Stromules induced during plant innate immunity dynamically interact and use the cytoskeleton to form and to direct the movement of chloroplasts.
    1. Cell Biology

    TRAIN (Transcription of Repeats Activates INterferon) in response to chromatin destabilization induced by small molecules in mammalian cells

    Katerina Leonova, Alfiya Safina ... Katerina Gurova
    Type I interferon signaling protects cells from the loss of epigenetic integrity, since it is activated in cells in response to accumulation of transcripts originating from normally silenced heterochromatin, caused by small-molecule-mediated nucleosome unfolding.
    1. Cell Biology
    2. Developmental Biology

    YAP and TAZ regulate adherens junction dynamics and endothelial cell distribution during vascular development

    Filipa Neto, Alexandra Klaus-Bergmann ... Holger Gerhardt
    Endothelial YAP/TAZ shape the developing vasculature by orchestrating mechanical inputs with BMP signalling to promote junctional VE-Cadherin turnover and cellular rearrangements.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Autocatalytic microtubule nucleation determines the size and mass of Xenopus laevis egg extract spindles

    Franziska Decker, David Oriola ... Jan Brugués
    Quantitative microscopy and theory show that the size of Xenopus laevis egg extract spindles is controlled by a spatially-regulated autocatalytic growth mechanism driven by microtubule-stimulated microtubule nucleation.
    1. Cell Biology
    2. Neuroscience

    Time- and polarity-dependent proteomic changes associated with homeostatic scaling at central synapses

    Christoph T Schanzenbächer, Julian D Langer, Erin M Schuman
    Metabolic labelling and quantitative proteomics reveal the temporal evolution of cellular and neuronal responses to global activity manipulations.
    1. Cell Biology

    NADPH oxidase mediates microtubule alterations and diaphragm dysfunction in dystrophic mice

    James Anthony Loehr, Shang Wang ... George G Rodney
    Reative oxygen species modulate microtubules and diaphragm function.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium

    Xiaowen Liu, Thuy Vien ... David E Clapham
    The primary cilia polycystin proteins, polycystin-1 and polycystin-2, affect cilia length in the kidney collecting duct epithelia, but only polycystin-2 is required for the functional ion channel in this organelle.
    1. Cell Biology
    2. Neuroscience

    KIF2A regulates the development of dentate granule cells and postnatal hippocampal wiring

    Noriko Homma, Ruyun Zhou ... Nobutaka Hirokawa
    Postnatal KIF2A is a key regulator for axon/dendrite determination of developing dentate granule cells, and its loss developed apical axons in dentate molecular layer, broke hippocampal wiring, and induced temporal lobe epilepsy.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Sorting of a multi-subunit ubiquitin ligase complex in the endolysosome system

    Xi Yang, Felichi Mae Arines ... Ming Li
    A single transmembrane E3 ligase complex can regulate protein ubiquitination at multiple organelles using interchangeable targeting subunits.
    1. Cell Biology
    2. Developmental Biology

    Cleavage activates Dispatched for Sonic Hedgehog ligand release

    Daniel P Stewart, Suresh Marada ... Stacey K Ogden
    Dispatched cleavage, mediated by Furin, regulates Dispatched membrane trafficking and release of Sonic Hedgehog ligand.