Browse our latest Cell Biology articles

A new structure reveals two Arf-GEF regulatory domains form a single structural unit that stimulates Arf-GEF activity.

Cell-cell junctions and the actin cytoskeleton are key players in the organisation and patterning of the extracellular matrix (ECM) on the apical side of tracheal cells.

A new resource quantifying the distribution of 5,000 individual proteins between nucleus and cytoplasm, as well as identifying 2,800 yeast, human and frog proteins that are exported from the nucleus by the exportin CRM1/Xpo1.

Directional switching of sister chromatids during mitosis is regulated by a mechanical clock that is sensitive to the stretch of centromeric chromatin between the chromatids.

A direct connection between distinct planar cell polarity systems orients cells, answering long-standing questions regarding the relationship between systems and the orientation of cell polarity.

Cholinergic system play an important role in waking-to-sleep cycles and in sleep stabilization.

Antagonistic signaling by the kinases PI3K and Itpkb limits the kinetics and enforces the Notch-dependence of beta-selection – the most important cell-fate determining process in alpha beta T cell development.

Signaling pathway mTOR can sense its principal activator amino acid arginine via a different mechanism than that previously described for other amino acids.

The budding yeast kinesin Kip2 is a polymerase that uses its processive motility in a positive feedback loop to promote microtubule growth.

Inactivation of the COPI vesicle coat in yeast reveals that COPI recycles early but not late Golgi proteins.