Browse our latest Cell Biology articles

Page 282 of 333
    1. Cancer Biology
    2. Cell Biology

    Rho-associated kinase (ROCK) function is essential for cell cycle progression, senescence and tumorigenesis

    Sandra Kümper, Faraz K Mardakheh ... Christopher J Marshall
    The Rho kinases ROCK1 and 2 act redundantly in regulating cell proliferation and their depletion causes cellular senescence.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    No current evidence for widespread dosage compensation in S. cerevisiae

    Eduardo M Torres, Michael Springer, Angelika Amon
    Dosage compensation does not take place in wild yeast strains.
    1. Cell Biology
    2. Computational and Systems Biology

    Active machine learning-driven experimentation to determine compound effects on protein patterns

    Armaghan W Naik, Joshua D Kangas ... Robert F Murphy
    In an investigation into the effects of drugs on proteins, an active machine learning algorithm chose which sets of experiments to perform and was able to learn an accurate model of the effects after doing only a fraction of the experiments.
    1. Cancer Biology
    2. Cell Biology

    Cell Proliferation: The ROCKs on which tumour cells thrive

    Simon Wilkinson, Margaret C Frame
    Version of Record
    Insight
    1. Cell Biology

    Novel origin of lamin-derived cytoplasmic intermediate filaments in tardigrades

    Lars Hering, Jamal-Eddine Bouameur ... Georg Mayer
    A newly discovered cytoplasmic intermediate filament in water bears may help these animals to resist extreme environmental conditions.
    1. Cell Biology
    2. Developmental Biology

    The beetle amnion and serosa functionally interact as apposed epithelia

    Maarten Hilbrant, Thorsten Horn ... Kristen A Panfilio
    Late morphogenesis of the insect extraembryonic epithelia involves transient formation of a basal-basal bilayer to coordinate the functional contributions of two discrete tissues.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Ternatin and improved synthetic variants kill cancer cells by targeting the elongation factor-1A ternary complex

    Jordan D Carelli, Steven G Sethofer ... Jack Taunton
    An ancient complex comprising the eukaryotic elongation factor-1A and aminoacylated tRNA is shown to be the target of a cyclic heptapeptide and two unrelated natural products with potent anticancer activity.
    1. Cell Biology
    2. Neuroscience

    Systematic substrate identification indicates a central role for the metalloprotease ADAM10 in axon targeting and synapse function

    Peer-Hendrik Kuhn, Alessio Vittorio Colombo ... Stefan F Lichtenthaler
    The metalloprotease ADAM10 modulates axon and synapse function by cleaving numerous synaptic and axonal membrane proteins in the central nervous system.
    1. Cell Biology
    2. Neuroscience

    The Melanocortin Receptor Accessory Protein 2 promotes food intake through inhibition of the Prokineticin Receptor-1

    Anna L Chaly, Dollada Srisai ... Julien A Sebag
    A non-melanocortin G-protein coupled receptor is inhibited by the Melanocortin Receptor Accessory Protein 2 (MRAP2) to control food intake in mammals.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Localized epigenetic silencing of a damage-activated WNT enhancer limits regeneration in mature Drosophila imaginal discs

    Robin E Harris, Linda Setiawan ... Iswar K Hariharan
    Localized silencing of damage-responsive enhancers can block regenerative growth while permitting those same genes to be used for normal development.