Browse our latest Cell Biology articles

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    1. Cell Biology

    Sperm Competition: Size isn't everything

    Ronald E Ellis, Qing Wei
    Version of Record
    Insight
    1. Cell Biology

    Lpcat3-dependent production of arachidonoyl phospholipids is a key determinant of triglyceride secretion

    Xin Rong, Bo Wang ... Peter Tontonoz
    The enzyme Lpcat3 plays a unique role in the incorporation of arachidonic acid into membranes, which is required for the production of lipoproteins.
    1. Cell Biology
    2. Developmental Biology

    FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis

    Melissa Kelley, John Yochem ... David S Fay
    A fibrillin-related protein, FBN-1, is a key component of the apical extracellular matrix and prevents epidermal cell deformation by biomechanical forces during morphogenesis of the C. elegans embryo.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Actin dynamics tune the integrated stress response by regulating eukaryotic initiation factor 2α dephosphorylation

    Joseph E Chambers, Lucy E Dalton ... Stefan J Marciniak
    Monomeric actin forms a crucial component of the eIF2α holophosphatase linking the integrated stress response to actin polymeric status.
    1. Cell Biology
    2. Cancer Biology

    Increased H+ efflux is sufficient to induce dysplasia and necessary for viability with oncogene expression

    Bree K Grillo-Hill, Changhoon Choi ... Diane L Barber
    Increasing the internal pH of cells can induce dysplasia and enhance oncogene-increased cell growth, while decreasing the internal pH combined with oncogene expression leads to synthetic lethality.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    The polarity protein Baz forms a platform for the centrosome orientation during asymmetric stem cell division in the Drosophila male germline

    Mayu Inaba, Zsolt G Venkei, Yukiko M Yamashita
    The stem cell orientation checkpoint senses the correct orientation of centrosomes via their interactions with a protein called Bazooka.
    1. Cell Biology

    No turnover in lens lipids for the entire human lifespan

    Jessica R Hughes, Vladimir A Levchenko ... Roger JW Truscott
    The carbon in lens membrane lipids correlates to the year of birth of an individual, a phenomenon that is unprecedented in the current body of literature.
    1. Cell Biology
    2. Plant Biology

    Auxin regulates SNARE-dependent vacuolar morphology restricting cell size

    Christian Löfke, Kai Dünser ... Jürgen Kleine-Vehn
    Vacuolar morphologenesis correlates with cell size and is required for auxin-dependent inhibition of growth.
    1. Cell Biology
    2. Neuroscience

    A library of MiMICs allows tagging of genes and reversible, spatial and temporal knockdown of proteins in Drosophila

    Sonal Nagarkar-Jaiswal, Pei-Tseng Lee ... Hugo J Bellen
    A large collection of functional EGFP tagged proteins derived from MiMIC insertions allows examination of protein expression in unfixed tissues and efficient tissue specific reversible knock down of proteins.
    1. Structural Biology and Molecular Biophysics
    2. Cell Biology

    Tuning myosin-driven sorting on cellular actin networks

    Rizal F Hariadi, Ruth F Sommese, Sivaraj Sivaramakrishnan
    Competition between the antagonistic motor proteins myosin V and myosin VI finely tunes unidirectional transport of cargo on different actin architectures.