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Changes in gene expression in cultured endothelial cells can be partially reversed by simulating in vivo conditions.

Stem cell heterogeneity is progressively built in proliferating population by the action of mitochondrial glutamine metabolism that opposes the cell cycle-linked self-renewal network to generate differentiation-competent progenitors.

Photodamaged chloroplasts are targeted for vacuolar degradation through microautophagy by the NBR1 autophagy receptor without the participation of the canonical autophagy machinery.

PLK-1 regulates multiple steps during oocyte meiosis I and is recruited to meiotic chromosomes through a dual mechanism involving BUB-1 and CENP-C.

Autofluorescence imaging permits label-free cell type identification in live airway tissue and reveals the dynamic formation of airway secretory cell associated antigen passages.

Genetic and chemical genetic analysis pinpoint defective epithelial cells as the driver for NPHP like phenotypes in Invs mutants, demonstrate genetic interaction between Invs and Ift88 and identify the HDAC inhibitor valproic acid as a suppressor for Invs mutant phenotypes.

Axon guidance genes are conserved regulators of neurodegeneration in Drosophila melanogaster and human inducible motor neuron models of UBQLN2-associated amyotrophic lateral sclerosis.

Zebrafish genetics and sperm cryo-electron tomography reveal a novel function of Calaxin as a docking complex component stabilizing the outer arm dynein onto the ciliary doublet microtubule.

The highly metabolically active hair cells of the zebrafish lateral line have a distinct mitochondrial phenotype consisting of small mitochondria apically and large, networked mitochondrion basally, demonstrating a nonuniform mitochondrial architecture that is sculpted by cellular activity.

Tie1 is a binding partner for Svep1 in zebrafish and humans, and both genes (but not Tie2) are required during zebrafish lymphangiogenesis especially for the facial lymphatics, which in part develop independent of Vegfc.