Browse our latest Cell Biology articles

Page 77 of 322
    1. Cell Biology
    2. Developmental Biology

    Ephrin-B1 regulates the adult diastolic function through a late postnatal maturation of cardiomyocyte surface crests

    Clement Karsenty, Celine Guilbeau-Frugier ... Celine Galés
    Eprhin B1 in the cardiomyocyte regulates the maturation of the adult surface crest architecture and of the diastolic function during a late postnatal stage in rodents.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Mir155 regulates osteogenesis and bone mass phenotype via targeting S1pr1 gene

    Zhichao Zheng, Lihong Wu ... Janak L Pathak
    Mir155 showed a catabolic effect on osteogenesis and bone mass phenotype via interaction with the S1pr1 gene, suggesting inhibition of Mir155 as a potential approach to bone regeneration and bone defect healing.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    A circular zone of attachment to the extracellular matrix provides directionality to the motility of Toxoplasma gondii in 3D

    Rachel V Stadler, Shane R Nelson ... Gary E Ward
    Parasites constrict as they propel themselves through the extracellular matrix one body length at a time, in a process highly reminiscent of host cell invasion.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration

    Amanda M Travis, Samiya Manocha ... Jillian N Pearring
    Dominant mutations in Arl3, linked to inherited retinal dystrophy, disrupt the active Arl3-GTP ciliary gradient and cause a defect in rod photoreceptor nuclear migration that can be rescued by elevating ciliary Arl3 activity or reducing aberrant non-ciliary Arl3 activity.
    1. Cell Biology
    2. Chromosomes and Gene Expression

    Adaptation to glucose starvation is associated with molecular reorganization of the circadian clock in Neurospora crassa

    Anita Szőke, Orsolya Sárkány ... Krisztina Káldi
    Molecular timekeeping in Neurospora crassa is robust even under severe limitation of carbon sources and the efficient adaptation to changing nutrient availability is dependent on the positive component of the circadian clock.
    1. Cell Biology
    2. Neuroscience

    Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones

    Chao Tan, Giovanni de Nola ... Pascal S Kaeser
    Hextuple knockout of key active zone proteins strongly reduces the pool of synaptic vesicles available for release, but synapse formation persists.
    1. Cell Biology

    A remarkable adaptive paradigm of heart performance and protection emerges in response to marked cardiac-specific overexpression of ADCY8

    Kirill V Tarasov, Khalid Chakir ... Edward G Lakatta
    Overexpression of hAC8 engages complex, coordinate adaptation 'circuity' that has evolved in mammalian cells to defend against stress that threatens health or life, and may be important for proper healing in disease states such as heart infarction or failure.
    1. Cell Biology
    2. Computational and Systems Biology

    Patterns of interdivision time correlations reveal hidden cell cycle factors

    Fern A Hughes, Alexis R Barr, Philipp Thomas
    Bayesian inference identifies hidden dynamics underlying noisy cell division data.
    1. Cell Biology

    Specific deletion of Axin1 leads to activation of β-catenin/BMP signaling resulting in fibular hemimelia phenotype in mice

    Rong Xie, Dan Yi ... Di Chen
    Specific gene knockout and signaling inhibition studies indicate the activation of β-catenin-bone morphogenetic protein signaling contributes to the development of fibular hemimelia disease.
    1. Cell Biology
    2. Physics of Living Systems

    Fixation can change the appearance of phase separation in living cells

    Shawn Irgen-Gioro, Shawn Yoshida ... Shasha Chong
    Different fixation protocols can both enhance and diminish the appearance of liquid–liquid phase separation (LLPS) droplets presenting a caveat in using fixed-cell imaging to diagnose LLPS.