Felix F Fuchsberger, Dongyoon Kim ... Christoph Rademacher
The information stored in glycans is interpreted and read by cell surface-exposed lectin receptors, and with information theory, the formal framework is set for how to analyze such complex single-cell data.
Development of nanoluciferase complementation-based tau biosensors to detect tau conformational change and oligomerization in living cells in high-throughput assays.
Combining live imaging and advanced electron microscopy gives insights into the structural integrity of the nematode epidermis and its intimate connection with the extracellular matrix.
Niels JM Verstegen, Sabrina Pollastro ... S Marieke van Ham
Single-cell RNA sequencing provides a detailed understanding of the cues controlling in vitro differentiation of human B cells into antibody-secreting cells (ASCs), uncovering a novel pre-ASC population present ex vivo in lymphoid tissues that progress through a germinal center-like state.
Francisco Prieto-Ruiz, Elisa Gómez-Gil ... José Cansado
A highly sophisticated and adaptive interplay between modulation of myosin II function by light chain phosphorylation and environmentally controlled formin availability, is critical for a successful cytokinesis during respiratory carbohydrate metabolism in the fission yeast Schizosaccharomyces pombe.
The hagfish slime glands, which produce a large volume of defensive slime within 0.4 s by ejecting threads and mucus into seawater, evolved from cells and genes expressed in the skin.
Gene knockout in cell lines and mice reveal that store-operated calcium entry is synergistically mediated by Orai1 and Orai3 channel proteins in B cells and is important for signaling to the nucleus and metabolic activity in response to antigenic stimulation.
