Cell Biology

Latest articles

1. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Optogenetic activation of heterotrimeric G-proteins by LOV2GIVe, a rationally engineered modular protein

   Mikel Garcia-Marcos et al.

   LOV2GIVe allows to activate Gi proteins non-invasively with innocuous blue light based on a design principle unrelated to light-activated GPCRs (metazoan opsins), thereby expanding the range of potential experimental applications.
2. 1. Cell Biology
   2. Plant Biology

   A cross-kingdom conserved ER-phagy receptor maintains endoplasmic reticulum homeostasis during stress

   Madlen Stephani et al.

   C53 bridges selective autophagy with ribosome-associated quality control at the endoplasmic reticulum.
3. 1. Cell Biology
   2. Chromosomes and Gene Expression

   Large domains of heterochromatin direct the formation of short mitotic chromosome loops

   Maximilian H Fitz-James et al.

   Large regions of foreign DNA inserted into mammalian chromosomes assemble into H3K9me3-heterochromatin and result in increased condensin loading with organisation into shorter mitotic chromosome loops than endogenous DNA.
4. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Molecular mechanism for direct actin force-sensing by α-catenin

   Lin Mei et al.
5. 1. Cell Biology

   Atg1 kinase in fission yeast is activated by Atg11-mediated dimerization and cis-autophosphorylation

   Zhao-Qian Pan et al.

   A mechanistic dissection of how autophagy kinase Atg1 is activated in fission yeast reveals surprising differences from the known Atg1 activation mechanisms previously defined in budding yeast.
6. 1. Cell Biology
   2. Microbiology and Infectious Disease

   Stress-activated MAPK signaling controls fission yeast actomyosin ring integrity by modulating formin For3 levels

   Elisa Gómez-Gil et al.

   Microscopic and biochemical analysis show that the stress-activated MAP kinase pathway targets the formin For3 to modulate actomyosin ring integrity in response to environmental cues.
7. 1. Cell Biology
   2. Developmental Biology

   Alstrom syndrome gene is a stem cell-specific regulator of centriole duplication in the Drosophila testis

   Cuie Chen, Yukiko M Yamashita
8. 1. Cell Biology
   2. Physics of Living Systems

   Stoichiometric interactions explain spindle dynamics and scaling across 100 million years of nematode evolution

   Reza Farhadifar et al.

   Stoichiometric interactions between microtubules and cortical force-generators set spindle size, position and dynamics, and its scaling with cell size in nematode species.
9. 1. Cell Biology
   2. Developmental Biology

   Live imaging of hair bundle polarity acquisition demonstrates a critical timeline for transcription factor Emx2

   Yosuke Tona, Doris K Wu
10. 1. Biochemistry and Chemical Biology
    2. Cell Biology

    Light-Regulated allosteric switch enables temporal and subcellular control of enzyme activity

    Mark Shaaya et al.