Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cancer Biology
    2. Cell Biology

    Exosomes: How tumors escape the immune system

    Stefanie Schmieder
    Mutations in the gene for β-catenin cause liver cancer cells to release fewer exosomes, which reduces the number of immune cells infiltrating the tumor.
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    1. Cell Biology
    2. Neuroscience

    Unraveling the link between neuropathy target esterase NTE/SWS, lysosomal storage diseases, inflammation, abnormal fatty acid metabolism, and leaky brain barrier

    Mariana I Tsap, Andriy S Yatsenko ... Halyna R Shcherbata
    Drosophila model reveals that NTE/SWS-associated neurodegeneration is a lysosomal storage disorder accompanied by a leaky brain permeability barrier, abnormal fatty acid metabolism, and inflammation.
    1. Cell Biology

    Microtubule-dependent orchestration of centriole amplification in brain multiciliated cells

    Amélie-Rose Boudjema, Rémi Balagué ... Alice Meunier
    1. Cancer Biology
    2. Cell Biology

    mTORC1/S6K1 signaling promotes sustained oncogenic translation through modulating CRL3IBTK-mediated ubiquitination of eIF4A1 in cancer cells

    Dongyue Jiao, Huiru Sun ... Kun Gao
    Overexpression of inhibitor of Bruton's tyrosine kinase contributes to the process of tumorigenesis by amplifying translation, represents a promising target for anti-cancer therapies.
    1. Cell Biology

    Genome concentration limits cell growth and modulates proteome composition in Escherichia coli

    Jarno Mäkelä, Alexandros Papagiannakis ... Christine Jacobs-Wagner
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    MEMO1 binds iron and modulates iron homeostasis in cancer cells

    Natalia Dolgova, Eva-Maria E Uhlemann ... Oleg Y Dmitriev
    Cancer metastasis modulator MEMO1 binds iron and is involved in regulating iron homeostasis in cancer cells.
    1. Cell Biology

    Transcriptomic profiling of Schlemm’s canal cells reveals a lymphatic-biased identity and three major cell states

    Revathi Balasubramanian, Krishnakumar Kizhatil ... Simon W.M. John

Senior editors

  1. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  2. David James
    University of Sydney, Australia
  3. Adèle L Marston
    University of Edinburgh, United Kingdom
  4. See more editors