Cell Biology

Latest articles

1. 1. Cell Biology

   Local activation of focal adhesion kinase orchestrates the positioning of presynaptic scaffold proteins and Ca²⁺ signalling to control glucose-dependent insulin secretion

   Dillon Jevon et al.

   The essential role of focal adhesion kinase in locally regulating insulin secretion and calcium responses in pancreatic beta cells is identified through the use of the pancreatic slice technique.
2. 1. Cell Biology

   C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9

   Saskia-Larissa Jauch-Speer et al.

   A genome-wide CRISPR/Cas9 knockout screening approach identified C/EBPδ as transcriptional regulator of the alarmins S100A8 and S100A9 during differentiation of monocytes and inflammatory processes in vivo.
3. 1. Biochemistry and Chemical Biology
   2. Cell Biology

   Role of oxidation of excitation-contraction coupling machinery in age-dependent loss of muscle function in Caenorhabditis elegans

   Haikel Dridi et al.

   The Ryanodine receptor type 1 calcium channels play a critical role in age-related muscle function loss.
4. 1. Cell Biology

   CLUH controls astrin-1 expression to couple mitochondrial metabolism to cell cycle progression

   Desiree Schatton et al.
5. 1. Cell Biology
   2. Physics of Living Systems

   Zebrafish airinemes optimize their shape between ballistic and diffusive search

   Sohyeon Park et al.

   Mathematical characterization of the shape of cellular protrusions that form cell–cell contacts in tissues reveals the parameters required for optimizing biological functional objectives, like maximizing cell–cell contact and communicating directional information.
6. 1. Cell Biology
   2. Neuroscience

   The organic cation transporter 2 regulates dopamine D1 receptor signaling at the Golgi apparatus

   Natasha M Puri et al.

   Dopamine D1 receptor signaling from the Golgi apparatus in murine striatal medium spiny neurons is regulated by monoamine transporter OCT2.
7. 1. Cell Biology

   Reducing lipid bilayer stress by monounsaturated fatty acids protects renal proximal tubules in diabetes

   Albert Pérez-Martí et al.
8. 1. Cell Biology
   2. Structural Biology and Molecular Biophysics

   Conserved structural elements specialize ATAD1 as a membrane protein extraction machine

   Lan Wang et al.
9. 1. Cell Biology

   OXPHOS deficiencies affect peroxisome proliferation by downregulating genes controlled by the SNF1 signaling pathway

   Jean-Claude Farre et al.

   The emerging importance of interorganellar communication is demonstrated by documentation of a feedback loop wherein peroxisome-generated metabolites affect mitochondrial ATP production and peroxisomal functions via signaling pathways requiring transmission of signals also through the cytosol and the nucleus.
10. 1. Cell Biology

    Macrophage inflammation resolution requires CPEB4-directed offsetting of mRNA degradation

    Clara Suñer et al.

    Decay rate of mRNAs encoding inflammatory regulators is controlled by the balance between AU-rich element-mediated deadenylation and cytoplasmic polyadenylation element-mediated polyadenylation.