Cell Biology

Cell Biology

eLife reviews research spanning vesicle transport and signal transduction to cell cycle and cell polarity and fate. Learn more about what we review and sign up for the latest content.
Illustration by Davide Bonazzi

Latest articles

    1. Cell Biology
    2. Developmental Biology

    Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

    Robert N Rainey, Sam D Houman ... Neil Segil
    Not revised
    Reviewed Preprint v1
    • Important
    • Compelling
    1. Cell Biology
    2. Developmental Biology

    Human formin FHOD3-mediated actin elongation is required for sarcomere integrity in cardiomyocytes

    Dylan A Valencia, Angela N Koeberlein ... Margot E Quinlan
    Complementary biochemical and cell-biological approaches reveal that formin FHOD3-mediated actin elongation, rather than nucleation, is critical for maintaining cardiomyocyte sarcomeres.
    1. Cell Biology
    2. Developmental Biology

    Female-germline specific protein Sakura interacts with Otu and is crucial for germline stem cell renewal and differentiation and oogenesis

    Azali Azlan, Li Zhu, Ryuya Fukunaga
    Sakura is expressed in female germlines, interacts with Otu, and is crucial for germline stem cell renewal and differentiation and oogenesis in Drosophila.
    1. Cell Biology
    2. Neuroscience

    PD-linked LRRK2 G2019S mutation impairs astrocyte morphology and synapse maintenance via ERM hyperphosphorylation

    Shiyi Wang, Ryan Baumert ... Cagla Eroglu
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Cell Biology

    The microbiome interacts with the circadian clock and dietary composition to regulate metabolite cycling in the Drosophila gut

    Yueliang Zhang, Sara B Noya ... Amita Sehgal
    The Drosophila microbiome regulates the cycling of gut metabolites in a circadian clock and diet-dependent manner.
    1. Cell Biology

    Forward genetics in C. elegans reveals genetic adaptations to polyunsaturated fatty acid deficiency

    Delaney Kaper, Uroš Radović ... Marc Pilon
    Polyunsaturated fatty acids are not genetically replaceable in the nematode C. elegans and only mutations that help free ferrous ions can boost the activity of a poorly functioning desaturase enzyme.
    1. Cell Biology

    Quantitative intra-Golgi transport and organization data suggest the stable compartment nature of the Golgi

    Hieng Chiong Tie, Haiyun Wang ... Lei Lu
    Quantitative measurements of intra-Golgi transport kinetics of diverse secretory cargos challenge the classic cisternal progression model and support the stable compartment model of the Golgi.
    1. Cell Biology

    Senescence: Returning aging cells to productivity

    Rachana S Vaidya, Simon Y Tang
    Platelet-derived growth factors can restore the proliferative potential of senescent cells taken from the degenerated intervertebral discs of aged humans.
    Version of Record
    Insight
    1. Cell Biology

    The molecular logic of Gtr1/2- and Pib2-dependent TORC1 regulation in budding yeast

    Jacob H Cecil, Cristina M Padilla ... Andrew P Capaldi
    Dual regulation of TORC1 by Gtr1/2 and Pib2 drives cells into three distinct signaling states, establishing a new paradigm for graded TORC1 signaling.

Senior editors

  1. Sofia J Araújo
    University of Barcelona, Spain
  2. Jonathan A Cooper
    Jonathan A Cooper
    Fred Hutchinson Cancer Research Center, United States
  3. David Ron
    Cambridge University, United Kingdom
  4. See more editors